Angeli-Besson C, Koeppel M C, Jacquet P, Andrac L, Sayag J
Department of Dermatology, CHU la Timone, Marseille, France.
Br J Dermatol. 1994 Mar;130(3):394-7. doi: 10.1111/j.1365-2133.1994.tb02940.x.
We report a case of scleredema adultorum (Buschke's disease) associated with an IgA kappa monoclonal hypergammaglobulinaemia. A significant improvement in the skin was obtained with electron-beam therapy. Scleredema would appear to be linked to monoclonal hypergammaglobulinaemia, but the relationship between the skin disorder and the immunoglobulin abnormality remains to be elucidated.
我们报告一例成人硬肿病（布施克病）合并IgA κ单克隆高丙种球蛋白血症。采用电子束治疗后皮肤有显著改善。硬肿病似乎与单克隆高丙种球蛋白血症有关，但皮肤疾病与免疫球蛋白异常之间的关系仍有待阐明。
