Rosner B, Prineas R, Daniels S R, Loggie J
Channing Laboratory, Harvard University, Boston, MA 02115, USA.
Am J Epidemiol. 2000 May 15;151(10):1007-19. doi: 10.1093/oxfordjournals.aje.a010129.
No large national studies of ethnic differences in blood pressure among children accounting for body size differences have been published, to the authors' knowledge. This report details the similarities and differences in systolic and diastolic blood pressures between Black children and White children in the United States and examines the effects of age, sex, and body size on ethnic differences in blood pressure levels. Standardized measurements of seated systolic and diastolic pressures from eight large epidemiologic studies published between 1978 and 1991 that included measurements of 47,196 children on 68,556 occasions for systolic pressure and for 38,184 children on 52,053 occasions for diastolic pressure were used; 51 percent (24,048 children) were boys and 37 percent (17,466 children) were Black. Overall, there appear to be few substantive ethnic differences in either systolic or diastolic pressure during childhood and adolescence. The differences that were observed were small, inconsistent, and often explained by differences in body size. There was an ethnic group-body mass index (BMI) interaction that resulted in these findings that at lower levels of BMI Blacks have higher blood pressure and more hypertension than do Whites, but that at the highest levels of BMI, Whites have more hypertension (systolic or diastolic pressure) than do Blacks.
据作者所知,尚未发表过考虑到体型差异的儿童血压种族差异的大型全国性研究。本报告详细阐述了美国黑人儿童和白人儿童收缩压和舒张压的异同,并研究了年龄、性别和体型对血压水平种族差异的影响。使用了1978年至1991年间发表的八项大型流行病学研究中坐位收缩压和舒张压的标准化测量数据,其中包括对47196名儿童进行了68556次收缩压测量,对38184名儿童进行了52053次舒张压测量;51%(24048名儿童)为男孩,37%(17466名儿童)为黑人。总体而言,儿童期和青少年期收缩压或舒张压似乎几乎没有实质性的种族差异。观察到的差异很小,不一致,而且往往可以用体型差异来解释。存在种族-体重指数(BMI)相互作用,导致这些结果,即在较低BMI水平时,黑人比白人血压更高、高血压更多,但在最高BMI水平时,白人比黑人有更多高血压(收缩压或舒张压)。