Thornhill S, Teasdale G M, Murray G D, McEwen J, Roy C W, Penny K I
Department of Neurosurgery, University of Glasgow, Southern General NHS Trust, Glasgow G51 4TF.
BMJ. 2000 Jun 17;320(7250):1631-5. doi: 10.1136/bmj.320.7250.1631.
To determine the frequency of disability in young people and adults admitted to hospital with a head injury and to estimate the annual incidence in the community.
Prospective, hospital based cohort study, with one year follow up of sample stratified by coma score.
Five acute hospitals in Glasgow.
2962 patients (aged 14 years or more) with head injury; 549 (71%) of the 769 patients selected for follow up participated.
Glasgow outcome scale and problem orientated questionnaire.
Survival with moderate or severe disability was common after mild head injury (47%, 95% confidence interval 42% to 52%) and similar to that after moderate (45%, 35% to 56%) or severe injury (48%, 36% to 60%). By extrapolation from the population identified (90% of whom had mild injuries), it was estimated that annually in Glasgow (population 909 498) 1400 young people and adults are still disabled one year after head injury.
The incidence of disability in young people and adults admitted with a head injury is higher than expected. This reflects the high rate of sequelae previously unrecognised in the large number of patients admitted to hospital with an apparently mild head injury.
确定因头部受伤入院的青少年和成年人的残疾发生率，并估计社区中的年发病率。
前瞻性、基于医院的队列研究，对按昏迷评分分层的样本进行为期一年的随访。
格拉斯哥的五家急症医院。
2962例头部受伤患者（年龄14岁及以上）；入选随访的769例患者中有549例（71%）参与。
格拉斯哥预后量表和问题导向问卷。
轻度头部受伤后中度或重度残疾存活很常见（47%，95%置信区间42%至52%），与中度（45%，35%至56%）或重度受伤后相似（48%，36%至60%）。根据已识别的人群（其中90%为轻度受伤）推断，估计在格拉斯哥（人口909498）每年有1400名青少年和成年人在头部受伤一年后仍有残疾。
因头部受伤入院的青少年和成年人的残疾发生率高于预期。这反映了在大量因明显轻度头部受伤入院的患者中，以前未被认识到的高后遗症发生率。
