里德-施特恩贝格细胞的超微结构研究。与转化淋巴细胞和组织细胞的比较。
Ultrastructural study of Reed-Sternberg cells. Comparison with transformed lymphocytes and histiocytes.
作者信息
Glick A D, Leech J H, Flexner J M, Collins R D
出版信息
Am J Pathol. 1976 Oct;85(1):195-208.
The ultrastructural features of Reed-Sternberg cells from 17 patients with Hodgkin's disease were compared with those of histiocytes and transformed lymphocytes in both benign and malignant conditions. Transformed lymphocytes and Reed-Sternberg cells appeared to have similar features, including large nuclei with dispersed chromatin, large nucleoli, and great numbers of cytoplasmic polyribosomes. Histiocytes contained abundant cytoplasmic lysosomal granules and microfilaments. These results are indicative of the origin of Reed-Sternberg cells from lymphocytes.
将17例霍奇金病患者的里德-施特恩贝格细胞的超微结构特征，与良性和恶性情况下的组织细胞及转化淋巴细胞的超微结构特征进行了比较。转化淋巴细胞和里德-施特恩贝格细胞似乎具有相似的特征，包括核大、染色质分散、核仁大以及大量胞质多核糖体。组织细胞含有丰富的胞质溶酶体颗粒和微丝。这些结果表明里德-施特恩贝格细胞起源于淋巴细胞。
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