异常淋巴细胞功能继发于药物诱导的自身免疫。
Abnormal lymphocyte function is secondary to drug-induced autoimmunity.
作者信息
Pugh S, Pelton B, Raftery E B, Denman A M
出版信息
Ann Rheum Dis. 1976 Aug;35(4):344-8. doi: 10.1136/ard.35.4.344.
Abstract
Abnormal lymphocyte function has been frequently reported in patients with connective tissue diseases but its significance has been uncertain. Sequential studies of lymphocyte function were carried out in patients receiving the beta-adrenergic blocking drug practolol (Eraldin) both before and during the development of autoimmune complications. No evidence was obtained that abnormal lymphocyte function presaged the onset of autoimmunity, and when these tests did show deficient responses these could be correlated with disease activity in general.
摘要
结缔组织病患者中常报告有淋巴细胞功能异常，但其意义尚不确定。在接受β-肾上腺素能阻断药物心得宁（普拉洛尔）治疗的患者中，在自身免疫并发症发生之前及期间对淋巴细胞功能进行了系列研究。没有证据表明异常的淋巴细胞功能预示着自身免疫的发作，而且当这些测试确实显示反应不足时，这些不足通常与疾病活动相关。
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