Behan P O, Behan W M, Zacharias F J, Nicholls J T
Lancet. 1976 Nov 6;2(7993):984-7. doi: 10.1016/s0140-6736(76)90831-x.
Patients with and without adverse reactions on practolol therapy showed altered immune responses. There was cutaneous anergy to Candida albicans and streptokinase/streptodornase antigens and depression of lymphocyte function in vitro. Anticomplementary activity and a wide range of autoantibodies were found in patients who had received practolol.