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1
Analysis of the function of a putative 2,3-diphosphoglyceric acid-dependent phosphoglycerate mutase from Bacillus subtilis.来自枯草芽孢杆菌的一种假定的2,3-二磷酸甘油酸依赖性磷酸甘油酸变位酶功能分析。
J Bacteriol. 2000 Jul;182(14):4121-3. doi: 10.1128/JB.182.14.4121-4123.2000.
2
Cloning and nucleotide sequences of the genes encoding triose phosphate isomerase, phosphoglycerate mutase, and enolase from Bacillus subtilis.枯草芽孢杆菌磷酸丙糖异构酶、磷酸甘油酸变位酶和烯醇化酶编码基因的克隆及核苷酸序列
J Bacteriol. 1994 Jul;176(13):3903-10. doi: 10.1128/jb.176.13.3903-3910.1994.
3
Characterization of cofactor-dependent and cofactor-independent phosphoglycerate mutases from Archaea.古菌中依赖辅因子和不依赖辅因子的磷酸甘油酸变位酶的特性分析。
Extremophiles. 2007 Sep;11(5):647-57. doi: 10.1007/s00792-007-0094-x. Epub 2007 Jun 19.
4
The role of manganese in growth and sporulation of Bacillus subtilis.锰在枯草芽孢杆菌生长和孢子形成中的作用。
J Gen Microbiol. 1979 Jun;112(2):329-36. doi: 10.1099/00221287-112-2-329.
5
Phosphoglycerate mutase is a highly efficient enzyme without flux control in Lactococcus lactis.磷酸甘油酸变位酶是一种在乳酸乳球菌中没有通量控制的高效酶。
J Mol Microbiol Biotechnol. 2010;18(3):174-80. doi: 10.1159/000315458. Epub 2010 Jun 8.
6
The Wolbachia endosymbiont of Brugia malayi has an active phosphoglycerate mutase: a candidate target for anti-filarial therapies.马来布鲁线虫的沃尔巴克氏体共生菌具有一种活性磷酸甘油酸变位酶：抗丝虫病治疗的候选靶点。
Parasitol Res. 2009 Apr;104(5):1047-52. doi: 10.1007/s00436-008-1287-7. Epub 2008 Nov 29.
7
Mechanistic implications for Escherichia coli cofactor-dependent phosphoglycerate mutase based on the high-resolution crystal structure of a vanadate complex.基于钒酸盐复合物的高分辨率晶体结构对大肠杆菌辅因子依赖性磷酸甘油酸变位酶的作用机制研究
J Mol Biol. 2002 Mar 8;316(5):1071-81. doi: 10.1006/jmbi.2002.5418.
8
Phosphorylation-mediated regulation of the Bacillus anthracis phosphoglycerate mutase by the Ser/Thr protein kinase PrkC.磷酸化介导的苏氨酸/丝氨酸蛋白激酶 PrkC 对炭疽芽孢杆菌磷酸甘油酸变位酶的调节作用。
Biochem Biophys Res Commun. 2023 Jul 12;665:88-97. doi: 10.1016/j.bbrc.2023.04.039. Epub 2023 Apr 25.
9
Purification and properties of the manganese-dependent phosphoglycerate mutase of Bacillus subtilis.枯草芽孢杆菌锰依赖性磷酸甘油酸变位酶的纯化及性质
J Bacteriol. 1979 Feb;137(2):773-8. doi: 10.1128/jb.137.2.773-778.1979.
10
Identification and characterization of the cofactor-independent phosphoglycerate mutases of Dirofilaria immitis and its Wolbachia endosymbiont.鉴定和特性分析犬恶丝虫及其共生内共生菌沃尔巴克氏体的辅因子非依赖型磷酸甘油酸变位酶。
Vet Parasitol. 2011 Mar 22;176(4):350-6. doi: 10.1016/j.vetpar.2011.01.020. Epub 2011 Jan 19.

引用本文的文献

1
Lysine Phoshoglycerylation Is Widespread in Bacteria and Overlaps with Acylation.赖氨酸磷酸甘油酰化在细菌中广泛存在且与酰化作用重叠。
Microorganisms. 2024 Jul 30;12(8):1556. doi: 10.3390/microorganisms12081556.
2
Role of Spore Core Water Content and pH in the Accumulation and Utilization of Spores' Large 3-Phosphoglyceric Acid Depot, and the Crucial Role of This Depot in Generating ATP Early during Spore Germination.芽孢核心含水量和pH值在芽孢大量3-磷酸甘油酸贮库的积累与利用中的作用，以及该贮库在芽孢萌发早期产生ATP过程中的关键作用。
Microorganisms. 2023 Jan 12;11(1):195. doi: 10.3390/microorganisms11010195.
3
Evolution of bacterial phosphoglycerate mutases: non-homologous isofunctional enzymes undergoing gene losses, gains and lateral transfers.细菌磷酸甘油酸变位酶的进化：经历基因丢失、获得和横向转移的非同源同工酶。
PLoS One. 2010 Oct 26;5(10):e13576. doi: 10.1371/journal.pone.0013576.
4
Identification of isopentenol biosynthetic genes from Bacillus subtilis by a screening method based on isoprenoid precursor toxicity.通过基于类异戊二烯前体毒性的筛选方法从枯草芽孢杆菌中鉴定异戊烯醇生物合成基因。
Appl Environ Microbiol. 2007 Oct;73(19):6277-83. doi: 10.1128/AEM.00861-07. Epub 2007 Aug 10.
5
Characterization of cofactor-dependent and cofactor-independent phosphoglycerate mutases from Archaea.古菌中依赖辅因子和不依赖辅因子的磷酸甘油酸变位酶的特性分析。
Extremophiles. 2007 Sep;11(5):647-57. doi: 10.1007/s00792-007-0094-x. Epub 2007 Jun 19.
6
Structure and molecular mechanism of Bacillus anthracis cofactor-independent phosphoglycerate mutase: a crucial enzyme for spores and growing cells of Bacillus species.炭疽芽孢杆菌非辅因子依赖性磷酸甘油酸变位酶的结构与分子机制：芽孢杆菌属芽孢和生长细胞中的关键酶
Biophys J. 2007 Feb 1;92(3):977-88. doi: 10.1529/biophysj.106.093872. Epub 2006 Nov 3.
7
Structural and functional analysis of Rv3214 from Mycobacterium tuberculosis, a protein with conflicting functional annotations, leads to its characterization as a phosphatase.对结核分枝杆菌Rv3214（一种功能注释存在冲突的蛋白质）进行结构和功能分析，结果表明它是一种磷酸酶。
J Bacteriol. 2006 May;188(10):3589-99. doi: 10.1128/JB.188.10.3589-3599.2006.
8
A cofactor-dependent phosphoglycerate mutase homolog from Bacillus stearothermophilus is actually a broad specificity phosphatase.嗜热脂肪芽孢杆菌中一种依赖辅因子的磷酸甘油酸变位酶同源物实际上是一种广谱特异性磷酸酶。
Protein Sci. 2001 Sep;10(9):1835-46. doi: 10.1110/ps.15701.

本文引用的文献

1
TRANSFORMATION OF BIOCHEMICALLY DEFICIENT STRAINS OF BACILLUS SUBTILIS BY DEOXYRIBONUCLEATE.脱氧核糖核酸对枯草芽孢杆菌生化缺陷菌株的转化
Proc Natl Acad Sci U S A. 1958 Oct 15;44(10):1072-8. doi: 10.1073/pnas.44.10.1072.
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Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
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Mechanism of catalysis of the cofactor-independent phosphoglycerate mutase from Bacillus stearothermophilus. Crystal structure of the complex with 2-phosphoglycerate.嗜热脂肪芽孢杆菌不依赖辅因子的磷酸甘油酸变位酶的催化机制。与2-磷酸甘油酸复合物的晶体结构。
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Structure and mechanism of action of a novel phosphoglycerate mutase from Bacillus stearothermophilus.嗜热脂肪芽孢杆菌新型磷酸甘油酸变位酶的结构与作用机制
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The two analogous phosphoglycerate mutases of Escherichia coli.大肠杆菌的两种类似磷酸甘油酸变位酶。
FEBS Lett. 1999 Jul 23;455(3):344-8. doi: 10.1016/s0014-5793(99)00910-2.
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Structural studies on a 2,3-diphosphoglycerate independent phosphoglycerate mutase from Bacillus stearothermophilus.嗜热脂肪芽孢杆菌中一种不依赖2,3-二磷酸甘油酸的磷酸甘油酸变位酶的结构研究。
J Struct Biol. 1999 Jun 15;126(2):156-65. doi: 10.1006/jsbi.1999.4112.
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The role of the C-terminal region in phosphoglycerate mutase.磷酸甘油酸变位酶中C末端区域的作用。
Biochem J. 1999 Jan 1;337 ( Pt 1)(Pt 1):89-95.
8
The enzymatic activity of phosphoglycerate mutase from gram-positive endospore-forming bacteria requires Mn2+ and is pH sensitive.革兰氏阳性产芽孢细菌中磷酸甘油酸变位酶的酶活性需要Mn2+且对pH敏感。
Can J Microbiol. 1998 Aug;44(8):759-67. doi: 10.1139/cjm-44-8-759.
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The complete genome sequence of the gram-positive bacterium Bacillus subtilis.革兰氏阳性细菌枯草芽孢杆菌的全基因组序列。
Nature. 1997 Nov 20;390(6657):249-56. doi: 10.1038/36786.
10
Most of the propeptide is dispensable for stability and autoprocessing of the zymogen of the germination protease of spores of Bacillus species.芽孢杆菌属芽孢萌发蛋白酶的酶原的稳定性和自身加工过程中，大部分前肽是可有可无的。
J Bacteriol. 1997 Mar;179(5):1824-7. doi: 10.1128/jb.179.5.1824-1827.1997.

来自枯草芽孢杆菌的一种假定的2,3-二磷酸甘油酸依赖性磷酸甘油酸变位酶功能分析。

Analysis of the function of a putative 2,3-diphosphoglyceric acid-dependent phosphoglycerate mutase from Bacillus subtilis.

作者信息

Pearson C L, Loshon C A, Pedersen L B, Setlow B, Setlow P

机构信息

Department of Biochemistry, University of Connecticut Health Center, Farmington 06032, USA.

出版信息

J Bacteriol. 2000 Jul;182(14):4121-3. doi: 10.1128/JB.182.14.4121-4123.2000.

DOI:10.1128/JB.182.14.4121-4123.2000
PMID:10869096
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC94603/
Abstract

A Bacillus subtilis gene termed yhfR encodes the only B. subtilis protein with significant sequence similarity to 2, 3-diphosphoglycerate-dependent phosphoglycerate mutases (dPGM). This gene is expressed at a low level during growth and sporulation, but deletion of yhfR had no effect on growth, sporulation, or spore germination and outgrowth. YhfR was expressed in and partially purified from Escherichia coli but had little if any PGM activity and gave no detectable PGM activity in B. subtilis. These data indicate that B. subtilis does not require YhfR and most likely does not require a dPGM.

摘要

一个名为yhfR的枯草芽孢杆菌基因编码了枯草芽孢杆菌中唯一一种与2,3-二磷酸甘油酸依赖性磷酸甘油酸变位酶（dPGM）具有显著序列相似性的蛋白质。该基因在生长和芽孢形成过程中低水平表达，但缺失yhfR对生长、芽孢形成或孢子萌发及生长没有影响。YhfR在大肠杆菌中表达并部分纯化，但几乎没有PGM活性，在枯草芽孢杆菌中也未检测到PGM活性。这些数据表明枯草芽孢杆菌不需要YhfR，很可能也不需要dPGM。