Tak Yan Yu D
Int Arch Allergy Appl Immunol. 1976;51(6):671-80. doi: 10.1159/000231645.
Hydrocortisone at 10(-4)M concentration could inhibit the response of human lymphocytes to galactose oxidase stimulation. Removal of the hydrocortisone after 4 h of culture did not reverse this inhibition. On the other hand, removal of monocytes greatly enhanced it, so that it could be observed at 10(-6)M concentration. Next, tonsil cells were separated into two fractions relatively rich in either T or B cells. Both fractions could respond to galactose oxidase and the response could be inhibited by hydrocortisone.
浓度为10⁻⁴M的氢化可的松可抑制人淋巴细胞对半乳糖氧化酶刺激的反应。培养4小时后去除氢化可的松并不能逆转这种抑制作用。另一方面，去除单核细胞可大大增强这种抑制作用，以至于在浓度为10⁻⁶M时仍可观察到。接下来，扁桃体细胞被分离成相对富含T细胞或B细胞的两个部分。这两个部分都能对半乳糖氧化酶产生反应，且该反应可被氢化可的松抑制。
