1999年俄罗斯南部疫情期间两株西尼罗河病毒的分离
Isolation of two strains of West Nile virus during an outbreak in southern Russia, 1999.
作者信息
Lvov D K, Butenko A M, Gromashevsky V L, Larichev V P, Gaidamovich S Y, Vyshemirsky O I, Zhukov A N, Lazorenko V V, Salko V N, Kovtunov A I, Galimzyanov K M, Platonov A E, Morozova T N, Khutoretskaya N V, Shishkina E O, Skvortsova T M
机构信息
D.I.Ivanovsky Institute of Virology, Moscow.
出版信息
Emerg Infect Dis. 2000 Jul-Aug;6(4):373-6. doi: 10.3201/eid0604.000408.
Abstract
From July to September 1999, a widespread outbreak of meningoencephalitis associated with West Nile virus (Flavivirus, Flaviviridae) occurred in southern Russia, with hundreds of cases and dozens of deaths. Two strains of West Nile virus isolated from patient serum and brain-tissue samples reacted in hemagglutination-inhibition and neutralization tests with patients' convalescent-phase sera and immune ascites fluid from other strains of West Nile virus.
摘要
1999年7月至9月，俄罗斯南部发生了一场与西尼罗河病毒（黄病毒科黄病毒属）相关的广泛的脑膜脑炎疫情，出现了数百例病例和数十人死亡。从患者血清和脑组织样本中分离出的两株西尼罗河病毒，在血凝抑制试验和中和试验中，与患者恢复期血清以及来自其他西尼罗河病毒株的免疫腹水发生了反应。
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