来自木腐真菌Xylaria sp. BCC 1067的抗疟化合物。
Antiplasmodial compounds from the wood-decayed fungus Xylaria sp. BCC 1067.
作者信息
Isaka M, Jaturapat A, Kladwang W, Punya J, Lertwerawat Y, Tanticharoen M, Thebtaranonth Y
出版信息
Planta Med. 2000 Jun;66(5):473-5. doi: 10.1055/s-2000-8588.
PMID:10909272
Abstract
Bioassay-guided fractionation of the extract from the wood-decayed fungus Xylaria sp. BCC 1067 led to the isolation of five antiplasmodial compounds, (-)-depudecin, (+)-phaseolinone, (+)-phomenone, 19,20-epoxycytochalasin Q, and (E)-methyl 3-(4-methoxyphenoxy)propenoate. These structures were elucidated using spectroscopic methods, especially NMR analysis.
摘要
对木腐真菌Xylaria sp. BCC 1067提取物进行生物测定导向的分级分离，得到了五种抗疟化合物，即（-）-去氢枞酸、（+）-菜豆素酮、（+）-鬼笔环肽、19,20-环氧细胞松弛素Q和（E）-3-（4-甲氧基苯氧基）丙烯酸甲酯。这些结构通过光谱方法，特别是核磁共振分析得以阐明。
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