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[抗加氏疏螺旋体抗体在莱姆病诊断中的应用]

[Antibodies against Borrelia garinii in diagnosis of Lyme disease].

作者信息

Flisiak R, Prokopowicz D

机构信息

Klinika Obserwacyjno-Zakaźna Akademii Medycznej w Białymstoku.

出版信息

Przegl Lek. 2000;57(3):147-9.

Abstract

Prevalence of antibodies against Borrelia garinii (Bg) was analysed in sera of 42 patients with Lyme borreliosis confirmed through demonstration of antibodies against antigen 41 kDa of Borrelia burgdorferi sensu stricto (Bbss). IgM or IgG antibodies against Bg were found in sera of 88% patients. Agreement of the results between Bg and Bbss tests related to IgM antibodies reached 84% and to IgG antibodies 76%. Comparison of individual results revealed significant positive correlation of optical densities in respect to both IgM and IgG antibodies. These results indicate possible use of detection of anti-Borrelia garinii antibodies in diagnostics of Lyme borreliosis in Poland.

摘要

通过检测抗狭义伯氏疏螺旋体(Bbss)41 kDa抗原的抗体确诊为莱姆病的42例患者血清中,分析了抗伽氏疏螺旋体(Bg)抗体的流行情况。88%的患者血清中发现了抗Bg的IgM或IgG抗体。与IgM抗体相关的Bg和Bbss检测结果的一致性达到84%,与IgG抗体相关的一致性为76%。个体结果比较显示,IgM和IgG抗体的光密度之间存在显著正相关。这些结果表明,检测抗伽氏疏螺旋体抗体可能用于波兰莱姆病的诊断。

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