Green R J, Frazier R A, Shakesheff K M, Davies M C, Roberts C J, Tendler S J
Laboratory of Biophysics and Surface Analysis, School of Pharmaceutical Sciences, The University of Nottingham, University Park, UK.
Biomaterials. 2000 Sep;21(18):1823-35. doi: 10.1016/s0142-9612(00)00077-6.
Surface plasmon resonance (SPR) is an optical technique that is widely gaining recognition as a valuable tool to investigate biological interactions. SPR offers real time in situ analysis of dynamic surface events and, thus, is capable of defining rates of adsorption and desorption for a range of surface interactions. In this review we highlight the diversity of SPR analysis. Examples of a wide range of applications of SPR are presented, concentrating on work relevant to the analysis of biomaterials. Particular emphasis is given to the use of SPR as a complimentary tool, showing the broad range of techniques that are routinely used alongside SPR analysis.
表面等离子体共振（SPR）是一种光学技术，作为研究生物相互作用的重要工具正日益受到广泛认可。SPR能够对动态表面事件进行实时原位分析，因此能够确定一系列表面相互作用的吸附和解吸速率。在本综述中，我们重点介绍了SPR分析的多样性。文中展示了SPR广泛应用的实例，重点关注与生物材料分析相关的研究。特别强调了将SPR用作辅助工具的情况，展示了通常与SPR分析一起使用的广泛技术。
