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用于微生物检测的纳米材料基传感器:综述

Nanomaterial-based sensors for microbe detection: a review.

作者信息

Khan Muhammad Qamar, Khan Jahangir, Alvi Muhammad Abbas Haider, Nawaz Hifza, Fahad Muhammad, Umar Muhammad

机构信息

Department of Textile Engineering, School of Engineering and Technology, National Textile University, Faisalabad, 37610, Punjab, Pakistan.

Department of Materials, The University of Manchester, Manchester, M13 9PL, UK.

出版信息

Discov Nano. 2024 Jul 30;19(1):120. doi: 10.1186/s11671-024-04065-x.

Abstract

Airborne microorganisms pose a significant health threat, causing various illnesses. Traditional detection methods are often slow and complex. This review highlights the potential of nanomaterial-based biosensors, particularly colorimetric sensors, for rapid and on-site detection of airborne microbes. Colorimetric sensors offer real-time visual detection without complex instrumentation. We explore the integration of these sensors with Lab-on-a-Chip technology using PDMS microfluidics. This review also proposes a novel PDMS-based colorimetric biosensor for real-time detection of airborne microbes. The sensor utilizes a color change phenomenon easily observable with the naked eye, simplifying analysis and potentially enabling point-of-care applications.

摘要

空气传播的微生物对健康构成重大威胁,会引发各种疾病。传统的检测方法往往既缓慢又复杂。本综述强调了基于纳米材料的生物传感器,特别是比色传感器,在快速现场检测空气传播微生物方面的潜力。比色传感器无需复杂仪器即可进行实时视觉检测。我们探讨了使用聚二甲基硅氧烷(PDMS)微流体技术将这些传感器与芯片实验室技术集成。本综述还提出了一种新型的基于PDMS的比色生物传感器,用于实时检测空气传播的微生物。该传感器利用肉眼易于观察到的颜色变化现象,简化了分析过程,并有可能实现即时护理应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05a0/11289191/5ee0701b2e08/11671_2024_4065_Fig1_HTML.jpg

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