Wigfield A S
Br J Vener Dis. 1975 Feb;51(1):54-6. doi: 10.1136/sti.51.1.54.
A 24-hr regimen of nimorazole (1 g. orally at 12-hrly intervals for three doses) was compared with metronidazole (200 mg. three times daily for 7 days) in the treatment of trichomonal vaginitis. The two treatment schedules were given to alternate patients, pregnant women being excluded. One hundred cases were treated on each schedule; roughly one-fifth of the patients in each group defaulted. There were no observed failures with either schedule. The reasons for these exceptionally good results are discussed.
将硝唑咪（1克，每12小时口服一次，共三剂）的24小时治疗方案与甲硝唑（每日三次，每次200毫克，共7天）用于治疗滴虫性阴道炎进行比较。两种治疗方案交替给予患者，孕妇除外。每种方案治疗100例患者；每组约五分之一的患者未坚持治疗。两种方案均未观察到治疗失败情况。文中讨论了取得这些异常良好结果的原因。
