• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Laboratory procedure for assessing specific locus mutations at the TK locus in cultured L5178Y mouse lymphoma cells.

作者信息

Clive D, Spector J F

出版信息

Mutat Res. 1975 Feb;31(1):17-29. doi: 10.1016/0165-1161(75)90059-x.

DOI:10.1016/0165-1161(75)90059-x
PMID:1093012
Abstract
摘要

相似文献

1
Laboratory procedure for assessing specific locus mutations at the TK locus in cultured L5178Y mouse lymphoma cells.评估培养的L5178Y小鼠淋巴瘤细胞中胸苷激酶（TK）基因座特定基因座突变的实验室程序。
Mutat Res. 1975 Feb;31(1):17-29. doi: 10.1016/0165-1161(75)90059-x.
2
Characteristics of spontaneous and induced thymidine and 5-iodo-2-deoxyuridine resistant clones of mouse lymphoma cells.小鼠淋巴瘤细胞自发和诱导产生的胸苷及5-碘-2-脱氧尿苷抗性克隆的特征
Mutat Res. 1974 Oct;25(1):89-105. doi: 10.1016/0027-5107(74)90222-x.
3
Analysis of trifluorothymidine-resistant (TFTr) mutants of L5178Y/TK+/- mouse lymphoma cells.L5178Y/TK+/-小鼠淋巴瘤细胞的三氟胸苷抗性（TFTr）突变体分析。
Mutat Res. 1985 Aug;151(1):161-74. doi: 10.1016/0027-5107(85)90194-0.
4
Characterization of thymidine kinase in L5178Y mouse lymphoma cells.L5178Y小鼠淋巴瘤细胞中胸苷激酶的特性研究
Toxicol Ind Health. 1985 Nov;1(3):1-12. doi: 10.1177/074823378500100301.
5
Cytogenetic characterization of the L5178Y TK+/-3.7.2C mouse lymphoma cell line.L5178Y TK+/-3.7.2C小鼠淋巴瘤细胞系的细胞遗传学特征
Mutat Res. 1985 Oct;147(5):243-53. doi: 10.1016/0165-1161(85)90065-2.
6
Thymidine kinase heterozygous L5178Y mouse lymphoma forward mutational assay.
J Assoc Off Anal Chem. 1978 May;61(3):609-11.
7
Viable chromosomal mutations affecting the TK locus in L5178Y/TK+/- mouse lymphoma cells: the other half of the assay.影响L5178Y/TK+/-小鼠淋巴瘤细胞中胸苷激酶（TK）基因座的存活染色体突变：检测的另一半
Ann N Y Acad Sci. 1983;407:253-7. doi: 10.1111/j.1749-6632.1983.tb47830.x.
8
High-resolution cytogenetic characterization of the L5178Y TK+/- mouse lymphoma cell line.
Mutat Res. 1989 Oct;214(2):181-93. doi: 10.1016/0027-5107(89)90162-0.
9
Sequence analysis of tka(-)-1 and tkb(+)-1 alleles in L5178Y tk+/- mouse-lymphoma cells and spontaneous tk-/- mutants.L5178Y tk+/-小鼠淋巴瘤细胞和自发tk-/-突变体中tka(-)-1和tkb(+)-1等位基因的序列分析。
Mutat Res. 1993 Apr;286(2):299-307. doi: 10.1016/0027-5107(93)90195-l.
10
Molecular dissection of mutations at the heterozygous thymidine kinase locus in mouse lymphoma cells.小鼠淋巴瘤细胞中杂合胸苷激酶基因座突变的分子剖析
Proc Natl Acad Sci U S A. 1990 Jan;87(1):51-5. doi: 10.1073/pnas.87.1.51.

引用本文的文献

1
Toxicological assessment of novel Anti-COVID traditional Chinese medicine formulae NRICM101 and NRICM102: a comprehensive study on safety and genotoxicity.新型抗新冠中药配方NRICM101和NRICM102的毒理学评估：安全性和遗传毒性的综合研究
Front Pharmacol. 2025 Sep 17;16:1596369. doi: 10.3389/fphar.2025.1596369. eCollection 2025.
2
Thymidine Kinase Mammalian Cell Mutagenicity Assays for Assessment of Nanomaterials.用于评估纳米材料的胸苷激酶哺乳动物细胞诱变性试验
Front Toxicol. 2022 Jun 8;4:864753. doi: 10.3389/ftox.2022.864753. eCollection 2022.
3
FR-900098, an antimalarial development candidate that inhibits the non-mevalonate isoprenoid biosynthesis pathway, shows no evidence of acute toxicity and genotoxicity.
FR-900098是一种抑制非甲羟戊酸类异戊二烯生物合成途径的抗疟候选药物，未显示出急性毒性和遗传毒性的证据。
Virulence. 2016 Aug 17;7(6):718-28. doi: 10.1080/21505594.2016.1195537. Epub 2016 Jun 3.
4
Preclinical and toxicology studies of 1263W94, a potent and selective inhibitor of human cytomegalovirus replication.1263W94（一种强效且选择性的人巨细胞病毒复制抑制剂）的临床前和毒理学研究。
Antimicrob Agents Chemother. 2002 Aug;46(8):2373-80. doi: 10.1128/AAC.46.8.2373-2380.2002.
5
Evaluation of the mutagenicity and carcinogenicity of motor vehicle emissions in short-term bioassays.通过短期生物测定评估机动车排放物的致突变性和致癌性。
Environ Health Perspect. 1983 Jan;47:141-52. doi: 10.1289/ehp.8347141.
6
Difference in metabolic profile of potassium canrenoate and spironolactone in the rat: mutagenic metabolites unique to potassium canrenoate.
Arch Toxicol. 1988 Jan;61(3):201-12. doi: 10.1007/BF00316635.
7
The genetic toxicity of 1,2-dibromo-3-chloropropane, 1,2-dibromo-3-chloro-2-methylpropane, and 1,2,3-tribromo-2-methylpropane.1,2 - 二溴 - 3 - 氯丙烷、1,2 - 二溴 - 3 - 氯 - 2 - 甲基丙烷和1,2,3 - 三溴 - 2 - 甲基丙烷的遗传毒性。
Cell Biol Toxicol. 1987 Dec;3(4):391-406. doi: 10.1007/BF00119912.
8
The genotoxicity of trenbolone, a synthetic steroid.
Arch Toxicol. 1988;61(4):249-58. doi: 10.1007/BF00364846.
9
Locus specificity in the mutability of L5178Y mouse lymphoma cells: the role of multilocus lesions.L5178Y小鼠淋巴瘤细胞突变性中的位点特异性：多位点损伤的作用
Proc Natl Acad Sci U S A. 1986 Jun;83(12):4379-83. doi: 10.1073/pnas.83.12.4379.
10
Inhibitory effects of quinolone antibacterial agents on eucaryotic topoisomerases and related test systems.喹诺酮类抗菌剂对真核拓扑异构酶的抑制作用及相关测试系统
Antimicrob Agents Chemother. 1990 Jan;34(1):8-12. doi: 10.1128/AAC.34.1.8.