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印度北部一家三级医疗中心的儿童中毒情况

Profile of childhood poisoning at a tertiary care centre in North India.

作者信息

Kohli Utkarsh, Kuttiat Vijesh Sreedhar, Lodha Rakesh, Kabra S K

机构信息

Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Indian J Pediatr. 2008 Aug;75(8):791-4. doi: 10.1007/s12098-008-0105-7. Epub 2008 Jun 25.

Abstract

OBJECTIVES

To determine the profile and outcome (discharge from emergency room after observation, admission or death) of pediatric patients presenting with acute poisoning to a tertiary care centre in north India.

METHODS

We retrospectively reviewed the last 2 year (July, 2004 to July, 2006) hospital records of pediatric emergency room to profile all cases of pediatric poisoning during that period and noted their outcome. All cases age < or = 12 years with definite history of poisoning were included.

RESULTS

111 patients presented to the pediatric emergency during the study period. Mean age of our patients was 3.12 +/- 2.04 yrs (SD). Majority of our patients (63.9%) was in the 1-3 yr age group. Males outnumbered females by a factor of two; majority of our patients resided in urban areas. Kerosene (27.9%), drugs (19.8%) and insecticides (11.7%) were the agents most frequently implicated. Almost all (96.9%) ingestions were accidental in nature. Thirty six patients (32.4%) were asymptomatic after 6 hr of observation in the emergency ward; 75 patients (67.6%) developed symptoms related to toxic ingestion. The common serious symptoms included altered sensorium, respiratory distress, seizures, ataxia, hypotension, cyanosis and burns; three patients required intubation and mechanical ventilation. Almost one third of our patients underwent gastric lavage; no patient with kerosene poisoning or any other inappropriate indication underwent the same.

CONCLUSION

The trends for pediatric poisoning noted at our centre are not very different from those observed in hospital-based studies conducted more than a decade ago, despite the rapid socioeconomic development in our country. In sharp contrast to developing countries, where majority of poisonings are due to common non-toxic household products, most of our patients require hospitalization because of severe symptoms related to dangerous nature of toxins ingested. Consultation with the poison cell results in improved patient management.

摘要

目的

确定印度北部一家三级护理中心收治的急性中毒儿科患者的概况及结局(观察后从急诊室出院、入院或死亡)。

方法

我们回顾性分析了过去2年(2004年7月至2006年7月)儿科急诊室的医院记录,以描述该期间所有儿科中毒病例的情况并记录其结局。纳入所有年龄≤12岁且有明确中毒史的病例。

结果

研究期间有111例患者到儿科急诊就诊。患者的平均年龄为3.12±2.04岁(标准差)。大多数患者(63.9%)年龄在1 - 3岁组。男性数量是女性的两倍;大多数患者居住在城市地区。煤油(27.9%)、药物(19.8%)和杀虫剂(11.7%)是最常涉及的中毒剂。几乎所有(96.9%)的摄入都是意外性质的。36例患者(32.4%)在急诊病房观察6小时后无症状;75例患者(67.6%)出现与中毒摄入相关的症状。常见的严重症状包括意识改变、呼吸窘迫、惊厥、共济失调、低血压、发绀和烧伤;3例患者需要插管和机械通气。几乎三分之一的患者接受了洗胃;没有煤油中毒或其他不适当指征的患者接受洗胃。

结论

尽管我国社会经济快速发展,但我们中心记录的儿科中毒趋势与十多年前开展的基于医院的研究中观察到的趋势并无太大差异。与发展中国家形成鲜明对比的是,在发展中国家大多数中毒是由常见的无毒家用产品引起的,而我们的大多数患者因摄入毒素的危险性导致严重症状而需要住院治疗。与中毒控制中心会诊可改善患者管理。

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