Limbos M M, Joyce D P, Chan C K, Kesten S
Toronto Lung Transplant Program,The Toronto Hospital, Ontario, Canada.
Chest. 2000 Aug;118(2):408-16. doi: 10.1378/chest.118.2.408.
The purpose of this study was to examine the psychological functioning and quality of life (QOL) of lung transplant candidates and recipients.
The following measures were completed by 36 lung transplant candidates (the pretransplant group [PRE]) and 73 recipients (the posttransplant group [POST]): the Rand-36 Item Health Survey 1.0 (RAND-36), visual analog scale of overall QOL (OQOL), Brief Symptoms Inventory (BSI), Derogatis Sexual Functioning Inventory (DSFI), Hospital Anxiety and Depression Scale (HAD), Rosenberg Self-Esteem Scale (RSES), and Body Cathexis Scale (BC).
Compared to the PRE, POST patients had significantly better scores on the following measures: RAND-36 total, physical health, role limitations due to physical health, general health, vitality, and social functioning subscales (all p < 0.0001); visual analog scale of OQOL (p < 0.0001); BSI (p < 0.05); BC (p < 0.05); HAD anxiety (p < 0.05) and depression (p < 0.0001); and RSES (p < 0.05). Despite better scores, some areas did not differ between the PRE and the POST, and many patients continued to experience impairments in psychological functioning. Specifically, the RAND-36 emotional health and role limitations due to emotional health subscale scores did not differ between the PRE and the POST and they remained lower than published norms. A significant proportion of patients in both groups (44% of PRE patients and 28% of POST patients) had borderline or clinical levels of anxiety (ie, the HAD). Finally, PRE and POST mean scores were significantly lower than published norms on the RSES (p < 0.05) and the body image scale of the DSFI (p < 0.05).
Although lung transplant recipients have better general, physical, and psychological health than their pretransplant counterparts, the present research suggests that both groups experience impairment in several areas of psychological functioning. Future research into the QOL of the lung transplant population should be aimed at recognizing, intervening, and improving patients' psychological and emotional well-being.
本研究旨在考察肺移植候选者及接受者的心理功能和生活质量（QOL）。
36名肺移植候选者（移植前组[PRE]）和73名接受者（移植后组[POST]）完成了以下测评：兰德36项健康调查1.0版（RAND - 36）、总体生活质量视觉模拟量表（OQOL）、简明症状量表（BSI）、德罗加蒂斯性功能量表（DSFI）、医院焦虑抑郁量表（HAD）、罗森伯格自尊量表（RSES）以及身体投入量表（BC）。
与移植前组相比，移植后组患者在以下测评中得分显著更高：RAND - 36总分、身体健康、因身体健康导致的角色受限、总体健康、活力以及社会功能分量表（均p < 0.0001）；OQOL视觉模拟量表（p < 0.0001）；BSI（p < 0.05）；BC（p < 0.05）；HAD焦虑（p < 0.
