Whitehead E
Can Med Assoc J. 1975 Jun 14;112(13 Spec No):89-90.
The combination trimethoprim-sulfamethoxazole was given in high dosage (four tablets twice daily) for either 2 or 5 days to 20 patients with sinusitis diagnosed on clinical grounds. In 11 the infection was improved or cured. Swabs cultured from 18 patients of the series produced no growth in 8. The organisms most likely to be isolated are Hemophilus influenzae and Diplococcus pneumoniae.
对20例临床诊断为鼻窦炎的患者给予大剂量复方新诺明(每日两次,每次四片),疗程为2天或5天。其中11例患者感染得到改善或治愈。该组18例患者的拭子培养物中,8例未培养出细菌。最可能分离出的病原体是流感嗜血杆菌和肺炎双球菌。