Eriguchi N, Aoyagi S, Hara M, Okuda K, Tamae T, Fukuda S, Hashino K, Hashimoto M, Sato S, Furukawa S, Fujiki K, Jimi A
Department of Surgery, Kurume University School of Medicine, Japan.
Kurume Med J. 2000;47(2):169-71. doi: 10.2739/kurumemedj.47.169.
Pancreatic cancer carries a poor prognosis, especially invasive ductal carcinoma of the pancreas. We present here the case of a 76-year-old man who developed synchronous double cancers of the stomach and pancreas. He was referred to our hospital in December, 1997, with a provisional diagnosis of carcinoma of the stomach. Laboratory data on admission showed normal levels except for the serum carcinoembryonic antigen level. Abdominal ultrasonography revealed a low echoic mass anterior to the pancreas, suggestive of a nodal metastasis. Intraoperative histological findings from the pancreatic nodule confirmed a primary pancreatic cancer. The diagnosis of double cancers of the stomach and pancreas was made, and subtotal gastrectomy and distal pancreatectomy with lymph nodes dissection were carried out. The histologic sections from the stomach showed a moderately differentiated tubular adenocarcinoma, whereas those from the pancreas showed a well to moderately differentiated tubular adenocarcinoma. Double carcinomas in this association are relatively rare.
胰腺癌预后较差,尤其是胰腺浸润性导管癌。我们在此报告一例76岁男性发生胃和胰腺同时性双癌的病例。1997年12月他因初步诊断为胃癌被转诊至我院。入院时实验室检查数据除血清癌胚抗原水平外均正常。腹部超声检查显示胰腺前方有一低回声肿块,提示淋巴结转移。胰腺结节的术中组织学检查结果证实为原发性胰腺癌。诊断为胃和胰腺双癌,并进行了胃次全切除术和远端胰腺切除术及淋巴结清扫术。胃的组织学切片显示为中分化管状腺癌,而胰腺的组织学切片显示为高分化至中分化管状腺癌。这种关联的双癌相对少见。