Nishimaki T, Kano K, Milgrom F
J Immunol. 1979 Jun;122(6):2314-8.
Heterophile, Hanganutziu-Deicher (H-D) antigen was studied in pathologic sera by means of inhibition of agglutination of bovine erythrocytes by H-D antibodies. H-D antigen was demonstrated in 38% of random cancer sera, 25% of lymphoma or leukemia sera, 25% of leprosy sera, 8% of infectious mononucleosis sera, 6% of rheumatoid arthritis sera, and 27% of synovial fluids of rheumatoid arthritis patients. None of 134 normal human sera gave positive results. Some of the inhibition-positive cancer sera formed precipitation lines with H-D antibody-containing sera. Over 50% of various extracts of cancer tissues as well as spleens of lymphoma or leukemia patients were shown to contain H-D antigen by means of the inhibition test.
通过Hanganutziu-Deicher（H-D）抗体对牛红细胞凝集的抑制作用，对病理性血清中的嗜异性H-D抗原进行了研究。在38%的随机癌症血清、25%的淋巴瘤或白血病血清、25%的麻风病血清、8%的传染性单核细胞增多症血清、6%的类风湿性关节炎血清以及类风湿性关节炎患者27%的滑液中检测到了H-D抗原。134份正常人血清均未得出阳性结果。部分抑制阳性的癌症血清与含H-D抗体的血清形成了沉淀线。通过抑制试验表明，超过50%的各种癌症组织提取物以及淋巴瘤或白血病患者的脾脏含有H-D抗原。
