Foss G L, Fotherby K
Curr Med Res Opin. 1975;3(2):72-6. doi: 10.1185/03007997509113650.
A combination of 150 mug. d-norgestrel with 30 mug. ethinyl oestradiol was administered to 120 women for a total of 767 cycles. No pregnancies occurred and cycle control was good, 99% of the cycles being within the range of 28 plus or minus 3 days. Breakthrough bleeding occurred in 7.2% of the cycles, spotting in 8.9% and amenorphoea in 0.8%. Side-effects were minimal.
将150微克炔诺孕酮与30微克炔雌醇联合使用,对120名女性进行了总共767个周期的给药。未发生妊娠,月经周期控制良好,99%的周期在28加减3天的范围内。突破性出血发生在7.2%的周期中,点滴出血发生在8.9%的周期中,闭经发生在0.8%的周期中。副作用极小。