Xiaoge D, Eryuan L, Xianping W, Zhiguang Z, Gan H, Zaijing J, Xiaoli P, Hongzhuan T, Hanwen W
Institute of Metabolism & Endocrinology, Second Affiliated Hospital of Hunan Medical University, Changsha, Hunan 410011, P. R. China.
Calcif Tissue Int. 2000 Sep;67(3):195-8. doi: 10.1007/s002230001139.
The incidence of hip fracture is lower in Chinese women compared with those from western countries, though they usually have lower bone mineral density (BMD). In this study, reference data (from Caucasian women) supplied by the manufacturer of Hologic Inc. was compared with data obtained from healthy women in Changsha, Hunan province, P.R.C. A total of 1488 Chinese women aged 15-95 years were randomly chosen for the study. Measurements of BMD were taken at the hip by dual energy X-ray absorptiometry (DXA) (QDR 4500A, Hologic Inc., USA). The BMD and the BMD decrease rate were somewhat lower than reference curves at all age groups and all sites except for the femoral neck and Ward's triangle. Chinese women reached their peak BMD 5-10 years later than their counterparts, and had a lower BMD decrease rate for about 35 years after peak BMD was attained. The fact that Chinese women take longer time to reach peak BMD and have a lower BMD decrease rate at the neck and Ward's triangle after peak BMD is attained protects them against hip fractures, and is a phenomenon that needs to be studied in the future.
与西方国家的女性相比，中国女性髋部骨折的发生率较低，尽管她们的骨矿物质密度（BMD）通常较低。在本研究中，将Hologic公司制造商提供的参考数据（来自白种女性）与从中华人民共和国湖南省长沙市的健康女性获得的数据进行了比较。总共随机选择了1488名年龄在15 - 95岁的中国女性进行研究。通过双能X线吸收法（DXA）（QDR 4500A，美国Hologic公司）在髋部测量骨密度。除股骨颈和沃德三角区外，所有年龄组和所有部位的骨密度及骨密度降低率均略低于参考曲线。中国女性达到峰值骨密度的时间比西方女性晚5 - 10年，并且在达到峰值骨密度后约35年内骨密度降低率较低。中国女性达到峰值骨密度所需时间更长，且在达到峰值骨密度后股骨颈和沃德三角区的骨密度降低率较低，这一事实使她们不易发生髋部骨折，是一个未来需要研究的现象。
