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保留肾单位手术——50例患者的初步经验

[Nephron-sparing surgery--initial experience with 50 patients].

作者信息

Halachmi S, Kastin A, Moskovitz B, Nativ O

机构信息

Urology Dept., Bnai Zion Medical Center, Haifa.

出版信息

Harefuah. 1999 Jun 15;136(12):919-23, 1004.

Abstract

During recent years the use of the new imaging techniques, ultrasonography and computerized tomography, has increased. The accessibility to these methods has changed the pattern of detection of renal lesions. Over 90% of renal masses are now discovered incidentally, while investigating nonurological symptoms. Therefore, most lesions are discovered in their early stages. The gold-standard procedure for removing renal masses is radical nephrectomy, which ensures complete removal of an organ-confined lesion, but involves loss of functional tissue. This might be critical in patients with a single kidney, or reduced nephron function. There are several diseases characterized by multiple renal lesions, such as Von Hippel-Lindau and tuberous sclerosis in which radical treatment may lead to chronic dialysis in young patients. Nephron-sparing surgery was developed in order to preserve as much functional tissue as possible while removing safely any suspicious renal lesion. This new technique, not involving radical surgery, should be evaluated in cases of renal tumors for its ability to achieve the same cancer cures rates. We present our experience with our first 50 patients who underwent nephron-sparing surgery for removal of renal lesions.

摘要

近年来,新型成像技术——超声检查和计算机断层扫描的使用有所增加。这些方法的可及性改变了肾脏病变的检测模式。如今,超过90%的肾脏肿块是在对非泌尿系统症状进行检查时偶然发现的。因此,大多数病变在早期就被发现。切除肾脏肿块的金标准手术是根治性肾切除术,它能确保完全切除局限于器官内的病变,但会导致功能性组织的丧失。这对于单肾患者或肾单位功能减退的患者可能至关重要。有几种疾病的特征是多发性肾脏病变,如冯·希佩尔-林道病和结节性硬化症,在这些疾病中,根治性治疗可能会导致年轻患者慢性透析。保留肾单位手术的发展是为了在安全切除任何可疑肾脏病变的同时,尽可能多地保留功能性组织。这种不涉及根治性手术的新技术,应在肾肿瘤病例中评估其实现相同癌症治愈率的能力。我们介绍了我们首批50例接受保留肾单位手术切除肾脏病变患者的经验。

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