Maschke C, Rupp T, Hecht K
Robert Koch-Institute, Section: Environmental Medicine, Berlin, Germany.
Int J Hyg Environ Health. 2000 Mar;203(1):45-53. doi: 10.1078/S1438-4639(04)70007-3.
For every faculty of perception there is, according to the degree of irritation, a biochemical or psychobiological activation. This is also true for the perception of sound or noise. Initially, these processes allow for the adjustment of the organism to a changed situation (eustress). Prolonged effects of stressors may ultimately lead to regulatory disturbances and induce pathological processes (distress). The pathogenetic concept that psychobiological stresses (e.g. noise) may be connected with the well-known risk factors of cardiovascular diseases, through excitation of the central nervous system, is based on the known stress models. The central connective factors are the activation hormones of the adrenal gland, also referred to as stress hormones. From blood and urine parameters recorded in epidemiological and experimental studies under the influence of acute or chronic noise, a simplified model of the pathogenetic mechanism has been developed. Fundamental conditions for future assessing the "stress hormones" have been derived, by means of which premorbid conditions can be determined on a population or group basis.
对于每一种感知能力而言，根据刺激程度会产生生化或心理生物学激活。对于声音或噪音的感知也是如此。最初，这些过程使机体能够适应变化的情况（良性应激）。应激源的长期影响最终可能导致调节紊乱并引发病理过程（恶性应激）。心理生物学应激（如噪音）可能通过中枢神经系统兴奋与心血管疾病的已知危险因素相关联的发病机制概念，是基于已知的应激模型。主要的关联因素是肾上腺的激活激素，也称为应激激素。根据在急性或慢性噪音影响下的流行病学和实验研究中记录的血液和尿液参数，已建立了发病机制的简化模型。已得出未来评估“应激激素”的基本条件，借此可以在人群或群体基础上确定疾病前期状况。
