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台湾地区饮用水氯化与不良妊娠结局之间的关联。

Association between chlorination of drinking water and adverse pregnancy outcome in Taiwan.

作者信息

Yang C Y, Cheng B H, Tsai S S, Wu T N, Lin M C, Lin K C

机构信息

College of Health Science, Kaohsiung Medical University, Kaohsiung City, Taiwan.

出版信息

Environ Health Perspect. 2000 Aug;108(8):765-8. doi: 10.1289/ehp.00108765.

DOI:10.1289/ehp.00108765
PMID:10964797
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1638297/
Abstract

Chlorination has been the major means of disinfecting drinking water in Taiwan. The use of chlorinated water has been hypothesized to lead to several adverse birth outcomes, including low birth weight and preterm delivery. We performed a study to examine the relationship between the use of chlorinated water and adverse birth outcomes in Taiwan. The study areas included 14 chlorinating municipalities (CHMs), which were defined as municipalities in which > 90% of the municipal population was served by chlorinated water, and 14 matched nonchlorinating municipalities (NCHMs), defined as municipalities in which < 5% of the municipal population is served by chlorinated water. The CHMs and NCHMs were similar to one another in terms of level of urbanization and sociodemographic characteristics. The study population comprised 18,025 women residing in the 28 municipalities who had a first parity singleton birth between 1 January 1994 and 31 December 1996 and for which complete information on maternal age, education, gestational age, birth weight, and sex of the baby were available. The results of our study suggest that there was no association between consumption of chlorinated drinking water and the risk of low birth weight.

摘要

在台湾,氯化消毒一直是饮用水消毒的主要方式。据推测,使用氯化水会导致多种不良出生结局,包括低出生体重和早产。我们开展了一项研究,以探讨台湾地区氯化水的使用与不良出生结局之间的关系。研究区域包括14个采用氯化消毒的直辖市(CHMs),定义为90%以上的市人口使用氯化水的直辖市,以及14个匹配的非氯化消毒直辖市(NCHMs),定义为5%以下的市人口使用氯化水的直辖市。CHMs和NCHMs在城市化水平和社会人口特征方面彼此相似。研究人群包括居住在这28个直辖市的18025名妇女,她们在1994年1月1日至1996年12月31日期间首次单胎分娩,且可获得产妇年龄、教育程度、孕周、出生体重和婴儿性别的完整信息。我们的研究结果表明,饮用氯化水与低出生体重风险之间没有关联。

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本文引用的文献

1
Fluoride in drinking water and cancer mortality in Taiwan.台湾地区饮用水中的氟化物与癌症死亡率
Environ Res. 2000 Mar;82(3):189-93. doi: 10.1006/enrs.1999.4018.
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Water chlorination and birth defects.水氯化与出生缺陷。
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Trihalomethanes in public water supplies and adverse birth outcomes.公共供水系统中的三卤甲烷与不良出生结局
Epidemiology. 1999 May;10(3):233-7.
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Exposure to trihalomethanes and adverse pregnancy outcomes.接触三卤甲烷与不良妊娠结局
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Disinfection by-products and adverse pregnancy outcomes: what is the agent and how should it be measured?消毒副产物与不良妊娠结局:致病因子是什么以及应如何对其进行检测?
Epidemiology. 1998 Sep;9(5):479-81. doi: 10.1097/00001648-199809000-00001.
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Chlorination of drinking water and cancer mortality in Taiwan.
Environ Res. 1998 Jul;78(1):1-6. doi: 10.1006/enrs.1997.3823.
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