Drost W T, Henry G A, Meinkoth J H, Woods J P, Lehenbauer T W
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater 74078, USA.
Am J Vet Res. 2000 Sep;61(9):1016-20. doi: 10.2460/ajvr.2000.61.1016.
To quantitatively determine echogenicity of the liver and renal cortex in clinically normal cats.
17 clinically normal adult cats.
3 ultrasonographic images of the liver and the right kidney were digitized from video output from each cat. Without changing the ultrasound machine settings, an image of a tissue-equivalent phantom was digitized. Biopsy specimens of the right renal cortex and liver were obtained for histologic examination. Mean pixel intensities within the region of interest (ROI) on hepatic, renal cortical, and tissue-equivalent phantom ultrasonographic images were determined by histogram analysis. From ultrasonographic images, mean pixel intensities for hepatic and renal cortical ROI were standardized by dividing each mean value by the mean pixel intensity from the tissue-equivalent phantom.
The mean (+/- SD) standardized hepatic echogenicity value was 1.06 +/- 0.02 (95% confidence interval, 1.02 to 1.10). The mean standardized right renal cortical echogenicity value was 1.04 +/- 0.02 (95% confidence interval, 1.01 to 1.08). The mean combined standardized hepatic and renal cortical echogenicity value was 1.02 +/- 0.05 (95% confidence interval, 0.99 to 1.04).
Quantitative determination of hepatic and renal cortical echogenicity in cats is feasible, using histogram analysis, and may be useful for early detection of diffuse parenchymal disease and for serially evaluating disease progression.
定量测定临床健康猫肝脏和肾皮质的回声性。
17只临床健康的成年猫。
从每只猫的视频输出中数字化采集肝脏和右肾的3张超声图像。在不改变超声机器设置的情况下，数字化采集组织等效体模的图像。获取右肾皮质和肝脏的活检标本用于组织学检查。通过直方图分析确定肝脏、肾皮质和组织等效体模超声图像上感兴趣区域（ROI）内的平均像素强度。从超声图像中，通过将肝脏和肾皮质ROI的每个平均值除以组织等效体模的平均像素强度，对肝脏和肾皮质ROI的平均像素强度进行标准化。
肝脏回声性标准化平均值（±标准差）为1.06±0.02（95%置信区间，1.02至1.10）。右肾皮质回声性标准化平均值为1.04±0.02（95%置信区间，1.01至1.08）。肝脏和肾皮质回声性标准化合并平均值为1.02±0.05（95%置信区间，0.99至1.04）。
使用直方图分析对猫的肝脏和肾皮质回声性进行定量测定是可行的，可能有助于早期发现弥漫性实质疾病并连续评估疾病进展。
