White Jennifer, Gay John, Farnsworth Raelynn, Mickas Matt, Kim KwangGi, Mattoon John
Department of Veterinary Clinical Sciences, Washington State University, Pullman, WA, 99614.
Vet Radiol Ultrasound. 2014 Jul-Aug;55(4):428-34. doi: 10.1111/vru.12130. Epub 2013 Dec 20.
A large amount of overlap exists in the B-mode ultrasound appearance of normal and abnormal liver, spleen, and kidney tissues in cats. Therefore, invasive tissue sampling procedures remain the standard method for diagnosing diseases in these organs. The purpose of our study was to assess the feasibility of ultrasound elastography as a technique for improving noninvasive characterization of the feline liver, spleen, and kidneys. Elastography was performed on 10 unsedated, clinically healthy cats. Numeric (strain) values (0 = softest to 255 = firmest) assigned to color pixels within regions of interest resulted in median scores (interquartile ranges) of body wall, 207.50 (189.75-224.00); liver, 119.00 (105.00-138.25); spleen, 127.50 (121-00-142.00); right renal cortex, 83.50 (64.00-130.00); right renal near field, 125.50 (110.75-139.75); left renal cortex, 77.50 (52.00-116.25); and left renal near field, 126.00 (114.00-145.25). Strain values were not different between organs. Body wall median was the only significantly different value (P < 0.05). Strain ratio values of body wall:organ were as follows: liver, 1.76 (1.38-2.00); spleen, 1.68 (1.47-1.83); right renal cortex, 2.31 (1.61-3.15); right renal near field, 1.62 (1.41-2.01); left renal cortex, 2.66 (1.45-4.13); and left renal near field, 1.51 (1.29-1.89). Subjectively, hepatic and splenic parenchymal tissues were homogeneous in compressibility and similar in elasticity to one another. Renal cortical tissue was softer compared to medullary tissue. Findings indicated that ultrasound elastography is a feasible technique for objectively and subjectively characterizing the feline liver, spleen, and kidneys. Further research is needed in cats with confirmed diseases of these organs, to compare the diagnostic sensitivity of ultrasound elastography vs. B-mode ultrasonography.
猫正常和异常肝脏、脾脏及肾脏组织的B超表现存在大量重叠。因此，侵入性组织采样程序仍是诊断这些器官疾病的标准方法。我们研究的目的是评估超声弹性成像作为一种改善猫肝脏、脾脏和肾脏非侵入性特征描述技术的可行性。对10只未使用镇静剂的临床健康猫进行了弹性成像检查。感兴趣区域内彩色像素的数值（应变）值（0 = 最软至255 = 最硬）得出体壁的中位数分数（四分位间距）为207.50（189.75 - 224.00）；肝脏为119.00（105.00 - 138.25）；脾脏为127.50（121.00 - 142.00）；右肾皮质为83.50（64.00 - 130.00）；右肾近场为125.50（110.75 - 139.75）；左肾皮质为77.50（52.00 - 116.25）；左肾近场为126.00（114.00 - 145.25）。各器官之间的应变值无差异。体壁中位数是唯一有显著差异的值（P < 0.05）。体壁与器官的应变比值如下：肝脏为1.76（1.38 - 2.00）；脾脏为1.68（1.47 - 1.83）；右肾皮质为2.31（1.61 - 3.15）；右肾近场为1.62（1.41 - 2.01）；左肾皮质为2.66（1.45 - 4.13）；左肾近场为1.51（1.29 - 1.89）。主观上，肝脏和脾脏实质组织在可压缩性方面均匀，且弹性彼此相似。肾皮质组织比髓质组织软。研究结果表明，超声弹性成像是客观和主观描述猫肝脏、脾脏和肾脏的可行技术。对于这些器官确诊疾病的猫，还需要进一步研究，以比较超声弹性成像与B超的诊断敏感性。
