Falkner B, Sherif K, Michel S, Kushner H
Departments of Medicine and Pediatrics, Thomas Jefferson University, Walnut Towers, 211 S Ninth St, Suite 630, Philadelphia, PA 19107.
Arch Pediatr Adolesc Med. 2000 Sep;154(9):918-22. doi: 10.1001/archpedi.154.9.918.
To determine if blood pressure (BP) level is associated with dietary micronutrients in adolescents at risk for hypertension.
Adolescents aged 14 to 16 years, with BP higher than the 90th percentile on 2 separate measurements in a school setting, had diet assessments. A 24-hour intake recall was obtained on 180 students (108 boys and 72 girls). Folic acid intake was used as an index of fruit, vegetable, and whole grain intake; the high folate group had a folate intake greater than the recommended daily allowance and the low folate group had a folate intake less than the recommended daily allowance. Data were analyzed by 2-way analysis of variance.
Mean diastolic BP was significantly higher in the low folate vs the high folate group (boys: 72 vs. 67 mm Hg; girls: 76 vs. 73 mm Hg; P =.008). The difference in systolic blood pressure was not significant. There was no difference in body mass index between the diet groups. Sodium intake per 4184 kJ was not different. The low folate group had significantly lower intakes per 4184 kJ of potassium (P =.002), calcium (P = .001), magnesium (P<.001), and total intake of beta carotene, cholecalciferol, vitamin E, and all B vitamins.
Among adolescents at risk for hypertension, BP was lower in those with higher intakes of a combination of nutrients, including potassium, calcium, magnesium, and vitamins. Dietary benefits on BP observed on diets rich in a combination of nutrients derived from fruits, vegetables, and low-fat dairy products could contribute to primary prevention of hypertension when instituted at an early age.
确定血压水平是否与有高血压风险的青少年的膳食微量营养素有关。
对14至16岁、在学校环境中两次独立测量血压均高于第90百分位数的青少年进行饮食评估。对180名学生(108名男生和72名女生)进行了24小时饮食摄入量回忆调查。叶酸摄入量用作水果、蔬菜和全谷物摄入量的指标;高叶酸组的叶酸摄入量高于推荐每日摄入量,低叶酸组的叶酸摄入量低于推荐每日摄入量。数据采用双向方差分析。
低叶酸组的平均舒张压显著高于高叶酸组(男生:72 vs. 67 mmHg;女生:76 vs. 73 mmHg;P = 0.008)。收缩压差异不显著。饮食组之间的体重指数没有差异。每4184千焦的钠摄入量没有差异。低叶酸组每4184千焦的钾摄入量(P = 0.002)、钙摄入量(P = 0.001)、镁摄入量(P<0.001)以及β-胡萝卜素、胆钙化醇、维生素E和所有B族维生素的总摄入量均显著较低。
在有高血压风险的青少年中,摄入包括钾、钙、镁和维生素在内的多种营养素较多的人血压较低。富含水果、蔬菜和低脂乳制品中多种营养素的饮食对血压的有益作用,在早年实施时可能有助于高血压的一级预防。