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柔软生物电介质的光学可变形性

Optical deformability of soft biological dielectrics.

作者信息

Guck J, Ananthakrishnan R, Moon T J, Cunningham C C, Käs J

机构信息

Center for Nonlinear Dynamics, Department of Physics, University of Texas at Austin, Austin, Texas 78712, USA.

出版信息

Phys Rev Lett. 2000 Jun 5;84(23):5451-4. doi: 10.1103/PhysRevLett.84.5451.

DOI:10.1103/PhysRevLett.84.5451
PMID:10990966
Abstract

Two counterpropagating laser beams were used to significantly stretch soft dielectrics such as cells. The deforming forces act on the surface between the object and the surrounding medium and are considerably higher than the trapping forces on the object. Radiation damage is avoided since a double-beam trap does not require focusing for stable trapping. Ray optics was used to describe the stress profile on the surface of the trapped object. Measuring the total forces and deformations of well-defined elastic objects validated this approach.

摘要

使用两束反向传播的激光束来显著拉伸诸如细胞等柔软电介质。变形力作用于物体与周围介质之间的表面,且远高于作用在物体上的捕获力。由于双光束阱不需要聚焦就能实现稳定捕获,因此可避免辐射损伤。利用光线光学来描述被捕获物体表面的应力分布。对明确的弹性物体的总力和变形进行测量验证了该方法。

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