局部激光光凝治疗后糖尿病性黄斑水肿的视网膜功能

Retinal function in diabetic macular edema after focal laser photocoagulation.

作者信息

Greenstein V C, Chen H, Hood D C, Holopigian K, Seiple W, Carr R E

机构信息

Department of Ophthalmology, New York University School of Medicine, Columbia University, New York, New York 10016, USA.

出版信息

Invest Ophthalmol Vis Sci. 2000 Oct;41(11):3655-64.

PMID:11006264

Abstract

PURPOSE

To assess the effects of focal photocoagulation on retinal function in the macular and perimacular areas in patients with diabetes who have clinically significant macular edema.

METHODS

Eleven patients were assessed after focal laser treatment. Multifocal electroretinogram (ERG) and full-field ERG techniques were used to evaluate the effects of treatment on macular, paramacular, and peripheral retinal function. A modified visual field technique was used to obtain local threshold fields. The posttreatment results were compared with pretreatment results. Changes in local ERG response amplitudes and implicit times were calculated for each patient and presented as difference fields. The changes in local ERG responses were compared with the changes in local field sensitivity.

RESULTS

After treatment, the results of the psychophysical tests suggested little or no change in visual function, but changes in retinal function were observed with the multifocal ERG technique. Local ERG responses showed increases in implicit time and decreases in amplitude, compared with pretreatment values. Timing was affected more than amplitude.

CONCLUSIONS

The results suggest that focal treatment produces changes in retinal function, and these changes are not restricted to the treated macular area.

摘要

目的

评估局灶性光凝对患有具有临床意义的黄斑水肿的糖尿病患者黄斑及黄斑周围区域视网膜功能的影响。

方法

对11例患者进行局灶性激光治疗后进行评估。使用多焦视网膜电图（ERG）和全视野ERG技术评估治疗对黄斑、黄斑旁及周边视网膜功能的影响。采用改良视野技术获取局部阈值视野。将治疗后的结果与治疗前的结果进行比较。计算每位患者局部ERG反应振幅和隐含时间的变化，并以差异视野表示。将局部ERG反应的变化与局部视野敏感度的变化进行比较。