Cordova C M, Blanchard A, Cunha R A
Faculdade de Ciências Farmacêuticas da Universidade de São Paulo, Brazil.
J Clin Lab Anal. 2000;14(5):246-53. doi: 10.1002/1098-2825(2000)14:5<246::AID-JCLA8>3.0.CO;2-F.
We determined the prevalence of three emergent urogenital mycoplasma species (M. fermentans, M. penetrans, and M. genitalium) in comparison to the most common species (M. hominis and U. urealyticum). M. genitalium is probably the third most frequent agent of nongonococcal urethritis (NGU) in men. It has been suggested that M. fermentans and M. penetrans play a role in the development of AIDS. We analysed the urine and the urethral swab samples from 106 HIV-1 infected individuals (HIV group) and 110 HIV-negative patients with NGU (STD group) by using PCR and culture methods. M. genitalium was detected in 0.9% of the urine and in 1.9% of the urethral samples from the HIV group, compared to 9.1% found only in urethral swab samples from the STD group. M. fermentans was detected in 5.7% urethral swabs from the HIV group and in 0.9% from the STD group. M. penetrans was detected in 6.6% urine samples from the HIV group. M. hominis and U. urealyticum showed infection rates of 7.5 and 18.9% in the HIV group, and 0.9 and 13.6% in the STD group. Overall there was a higher prevalence of mycoplasmas in the HIV group than in the STD group, but the significance of these results remains unclear.
我们测定了三种泌尿生殖系统新兴支原体物种（发酵支原体、穿透支原体和生殖支原体）的流行率，并与最常见的物种（人型支原体和解脲脲原体）进行比较。生殖支原体可能是男性非淋菌性尿道炎（NGU）的第三大常见病原体。有人提出，发酵支原体和穿透支原体在艾滋病的发展中起作用。我们通过聚合酶链反应（PCR）和培养方法，分析了106例HIV-1感染个体（HIV组）和110例NGU的HIV阴性患者（性传播疾病组）的尿液和尿道拭子样本。HIV组中，0.9%的尿液样本和1.9%的尿道样本检测到生殖支原体，而性传播疾病组仅在尿道拭子样本中发现9.1%。HIV组5.7%的尿道拭子检测到发酵支原体，性传播疾病组为0.9%。HIV组6.6%的尿液样本检测到穿透支原体。HIV组中人型支原体和解脲脲原体的感染率分别为7.5%和18.9%，性传播疾病组分别为0.9%和13.6%。总体而言，HIV组支原体的流行率高于性传播疾病组，但这些结果的意义尚不清楚。
