Van Unnik J A, Breur K, Burgers J M, Cleton F, Hart A A, Kroese W F, Somers R, Van Turnhout J M
Br J Cancer Suppl. 1975 Mar;2:201-7.
An analysis is given of the clinico-pathological correlations of non-Hodgkin's lymphomata in 332 patients referred to the Netherlands Cancer Institute in Amsterdam and the Rotterdam Radiotherapy Institute. Clinical staging proved to be an important prognostic index. In Stage I the 5 year survival was 55%, in Stage II 25% and in Stages III and IV less than 10%. The presence of follicular structures in non-Hodgkin's lymphomata has similarly an important prognostic significance especially in Stage I and II. In lymphocytic lymphomata a larger cell size is correlated with less favourable prognosis. The presence of macrophages in non-Hodgkin's lymphomata is found in patients with short survival. The histiocytic lymphomata have a different survival pattern from the lymphocytic lymphomata in Stages I and II.
对332例转诊至阿姆斯特丹的荷兰癌症研究所和鹿特丹放射治疗研究所的非霍奇金淋巴瘤患者的临床病理相关性进行了分析。临床分期被证明是一个重要的预后指标。I期患者的5年生存率为55%，II期为25%，III期和IV期则低于10%。非霍奇金淋巴瘤中滤泡结构的存在同样具有重要的预后意义，尤其是在I期和II期。在淋巴细胞性淋巴瘤中，细胞体积较大与预后较差相关。在生存期短的非霍奇金淋巴瘤患者中发现有巨噬细胞。组织细胞性淋巴瘤在I期和II期的生存模式与淋巴细胞性淋巴瘤不同。
