Pedini V, Scocco P, Dall'Aglio C, Ceccarelli P, Gargiulo A M
Dipartimento di Scienze Biopatologiche Veterinarie, Sezione di Anatomia, Via San Costanzo 4, 06126 Perugia, Italy.
Res Vet Sci. 2000 Oct;69(2):159-63. doi: 10.1053/rvsc.2000.0407.
Sugar residues are important components of salivary gland secretion. Traditional histochemical methods and lectin histochemistry were used to characterise glycoconjugates present in the mandibular gland of normal adult pigs. Acinar cells contained abundant quantities of glycoconjugates with the terminal trisaccharide sialic acid - (alpha 2-->3, 6) galactosyl (beta 1-->3) N -acetylgalactosamine. Mandibular acinar cells also contained alpha and beta N -acetylgalactosamine and N -acetylglucosamine residues, whereas the demilunar cells contained glycoconjugates with fucose, mannose and N -acetylglucosamine residues. In the duct system a range of sugar residues were localised throughout the cell cytoplasm or limited to the apical surface. These results provide new knowledge concerning the structure of salivary glycoconjugates in normal adult pig and a basis for future pathological studies.
糖残基是唾液腺分泌物的重要组成部分。采用传统组织化学方法和凝集素组织化学对正常成年猪下颌腺中存在的糖缀合物进行表征。腺泡细胞含有大量带有末端三糖唾液酸 - (α2→3,6)半乳糖基(β1→3)N - 乙酰半乳糖胺的糖缀合物。下颌腺泡细胞还含有α和β N - 乙酰半乳糖胺以及N - 乙酰葡糖胺残基,而半月细胞含有带有岩藻糖、甘露糖和N - 乙酰葡糖胺残基的糖缀合物。在导管系统中,一系列糖残基定位于整个细胞质或局限于顶端表面。这些结果为正常成年猪唾液糖缀合物的结构提供了新知识,并为未来的病理学研究奠定了基础。