Lin S J, Hwang D F
Department of Food Science, National Taiwan Ocean University, Keelung, Taiwan.
Toxicon. 2001 Apr;39(4):573-9. doi: 10.1016/s0041-0101(00)00171-9.
The seasonal variations of toxicity and stomach contents in toxic starfish Astropecten scoparius were detected. The average highest specimen toxicity, expressed as tetrodotoxin (TTX), was 16,821 mouse units (MU). The toxin was composed of TTX only, except April's sample containing mainly TTX along with minor paralytic shellfish poisons. The composition in the stomach of less and more toxic starfish was mainly Veremolpa scabra and Umborium suturale, respectively. The toxicities of U. suturale and V. scabra, found in the starfish stomach were 65 and 33 MU, respectively. For those collected from the coastal waters, U. suturale was toxic with average toxicity value of 77 MU/g, but V. scabra was nontoxic. The toxin in the specimens of U. suturale collected from either the digestive gland of starfish or the coastal waters, was TTX and anhydroTTX only. It indicates that the starfish A. scoparius might mainly accumulate high amount of TTX from U. suturale. Furthermore, both small gastropods U. suturale and Natica psuestes are first reported to contain TTX.
检测了有毒海星粗糙海燕（Astropecten scoparius）毒性和胃内容物的季节性变化。以河豚毒素（TTX）表示的平均最高样本毒性为16,821小鼠单位（MU）。除4月的样本主要含有TTX以及少量麻痹性贝类毒素外，毒素仅由TTX组成。毒性较低和较高的海星胃中的成分分别主要是粗糙唇齿螺（Veremolpa scabra）和缝合翁戎螺（Umborium suturale）。在海星胃中发现的缝合翁戎螺和粗糙唇齿螺的毒性分别为65和33 MU。对于从沿海水域采集的样本，缝合翁戎螺有毒，平均毒性值为77 MU/g，但粗糙唇齿螺无毒。从海星消化腺或沿海水域采集的缝合翁戎螺样本中的毒素仅为TTX和脱水TTX。这表明粗糙海燕可能主要从缝合翁戎螺中积累大量TTX。此外，首次报道小型腹足动物缝合翁戎螺和拟奈特螺（Natica psuestes）含有TTX。
