Manevski A, Bertoni G, Bardet C, Tremousaygue D, Lescure B
Laboratoire de Biologie Moléculaire des Relations Plantes-Microorganismes, CNRS-INRA UMR 215, P.O. Box 27, 31326, Castanet-Tolosan, France.
FEBS Lett. 2000 Oct 13;483(1):43-6. doi: 10.1016/s0014-5793(00)02056-1.
The telo-box, an interstitial telomere motif, was shown to regulate gene expression in root meristems, in synergy with a cis-acting element involved in the activation of expression of plant eEF1A genes, encoding the translation elongation factor EF1A, and of several ribosomal protein genes. We demonstrate here that the telo-box is also required for transcription activation by two other cis elements present within the promoter of genes encoding the acidic ribosomal protein rp40 and the proliferating cell nuclear antigen respectively. The control of gene expression by telo-boxes during cell cycle progression in Arabidopsis root meristems is discussed. A parallel is drawn with the function of telomeric sequences in Saccharomyces cerevisiae.
端粒盒是一种中间端粒基序，已证明它与一种顺式作用元件协同作用，可调节根分生组织中的基因表达，该顺式作用元件参与激活植物eEF1A基因（编码翻译延伸因子EF1A）以及多个核糖体蛋白基因的表达。我们在此证明，分别存在于编码酸性核糖体蛋白rp40和增殖细胞核抗原的基因启动子内的另外两个顺式元件进行转录激活时，端粒盒也是必需的。本文讨论了拟南芥根分生组织细胞周期进程中端粒盒对基因表达的控制。文中还将其与酿酒酵母中端粒序列的功能进行了比较。
