Price T S, Freeman B, Craig I, Petrill S A, Ebersole L, Plomin R
Social Genetic and Developmental Psychiatry Research Centre, Institute of Psychiatry, London, UK.
Twin Res. 2000 Sep;3(3):129-33. doi: 10.1375/136905200320565391.
A parental report questionnaire posted to a population sample of 18-month-old twins correctly assigned zygosity in 95%of cases when validated against zygosity determined by identity of polymorphic DNA markers. The questionnaire was as accurate when readministered at 3 years of age, with 96% of children being assigned the same zygosity on both occasions. The results validate the use of parental report questionnaire data to determine zygosity in infancy.
一份发给18个月大双胞胎群体样本的家长报告问卷,在与通过多态性DNA标记的同一性确定的合子性进行验证时,在95%的案例中正确地确定了合子性。当在3岁时再次进行问卷调查时,其准确性相同,96%的儿童在两次调查中被确定为相同的合子性。这些结果证实了使用家长报告问卷数据来确定婴儿期合子性的有效性。