Miyoshi E, Fujino Y, Mashimo T, Nishimura M
Intensive Care Unit, Osaka University Hospital, Osaka, Japan.
Chest. 2000 Oct;118(4):1109-15. doi: 10.1378/chest.118.4.1109.
Transport ventilators with inspiratory triggering functions and pressure support-control modes have recently become commercially available. We evaluated these ventilators in comparison with a standard ICU ventilator.
Laboratory study with a mechanical lung model.
We compared the performance of four transport ventilators (model 740, Mallinckrodt, Pleasanton, CA; TBird, Bird Products Corp, Palm Springs, CA; LTV1000, Pulmonetic Systems, Colton, CA; Esprit, Respironics, Vista, CA) with a standard ICU ventilator (model 7200ae; Mallinckrodt) using a test lung that simulated spontaneous breathing (compliance, 46.8 mL/cm H(2)O; resistance, 5 cm H(2)O/L/s). The settings of ventilators were positive end-expiratory pressure (PEEP) of 0 or 5 cm H(2)O, and pressure support (PS) of 0 or 10 cm H(2)O. The settings of the test lung were inspiratory time of 1 s, respiratory rate of 10/min, peak inspiratory flow of 40, 60, and 80 L/min. To evaluate inspiratory function at each setting, we measured the inspiratory delay time (DT), inspiratory trigger pressure (P-I), and the time for airway pressure to rise from the baseline pressure to 90% of the end-inspiratory pressure (T(90%)); for expiratory function, supraplateau expiratory pressure (P-E) and the time constant (taue) for pressure decrease during exhalation were evaluated. Oxygen requirement was assessed as the time required to empty a 3.5-L oxygen tank.
For inspiratory triggering, four transport ventilators had DT < 100 ms, which is considered clinically satisfactory, in all the settings except for PS 0 cm H(2)O, PEEP 0 cm H(2)O, and inspiratory flow of 80 L/min with LTV1000. P-I increased only in LTV1000 when PEEP was increased from 0 to 5 cm H(2)O. taue for the transport ventilators was > 50% shorter than for the ICU ventilator except for PS 0 cm H(2)O and PEEP 5 cm H(2)O with TBird. Oxygen requirement was lowest for the Esprit, followed by the 740, LTV1000, and TBird.
The newer Food and Drug Administration-approved transport ventilators have performance indexes comparable to the ventilator currently used in ICUs and can probably be recommended for clinical use.
具有吸气触发功能和压力支持 - 控制模式的转运呼吸机最近已上市。我们将这些呼吸机与标准重症监护病房(ICU)呼吸机进行了评估比较。
使用机械肺模型的实验室研究。
我们使用模拟自主呼吸的测试肺(顺应性,46.8 mL/cm H₂O;阻力,5 cm H₂O/L/s),将四台转运呼吸机(型号740, Mallinckrodt,普莱森顿,加利福尼亚州;TBird,Bird Products Corp,棕榈泉,加利福尼亚州;LTV1000,Pulmonetic Systems,科尔顿,加利福尼亚州;Esprit,Respironics,维斯塔,加利福尼亚州)与一台标准ICU呼吸机(型号7200ae;Mallinckrodt)的性能进行了比较。呼吸机设置为呼气末正压(PEEP)为0或5 cm H₂O,压力支持(PS)为0或10 cm H₂O。测试肺的设置为吸气时间1 s,呼吸频率10次/分钟,吸气峰流速为40、60和80 L/min。为评估每种设置下的吸气功能,我们测量了吸气延迟时间(DT)、吸气触发压力(P - I)以及气道压力从基线压力升至吸气末压力90%所需的时间(T(90%));对于呼气功能,评估了平台期以上呼气压力(P - E)和呼气过程中压力下降的时间常数(taue)。氧气需求量评估为排空一个3.5 L氧气罐所需的时间。
对于吸气触发,除了LTV1000在PS为0 cm H₂O、PEEP为0 cm H₂O且吸气流量为80 L/min的设置外,四台转运呼吸机在所有设置下的DT均<100 ms,这在临床上被认为是令人满意的。当PEEP从0增加到5 cm H₂O时,仅LTV1000的P - I增加。除了TBird在PS为0 cm H₂O和PEEP为5 cm H₂O的情况外,转运呼吸机的taue比ICU呼吸机短>50%。Esprit的氧气需求量最低,其次是740、LTV1000和TBird。
美国食品药品监督管理局(FDA)新批准的转运呼吸机具有与目前ICU中使用的呼吸机相当的性能指标,可能推荐用于临床。