Budde W M, Jonas J B, Martus P, Gründler A E
Department of Ophthalmology, Friedrich-Alexander-University Erlangen-Nürnberg, Erlangen, Germany.
J Glaucoma. 2000 Oct;9(5):357-62. doi: 10.1097/00061198-200010000-00003.
To evaluate the influence of optic disc size on segmental neuroretinal rim area in healthy eyes.
The study included 193 eyes of 193 healthy patients with physiologic disc cupping. On 15 degrees color stereophotographic optic disc diapositives, optic disc area and neuroretinal rim area were morphometrically determined in 36 radial optic disc segments each measuring 10 degrees.
The correlations of segmental rim area to disc area were significantly strongest (P < 0.01) and the regression lines were steepest in the inferior disc region, and the values were lowest in the temporal disc region. Complementary to the rim data, the correlations of segmental cup area to disc area were significantly strongest (P < 0.01) and the regression lines were steepest in the temporal disc region, and the values were lowest in the inferior disc region. In comparison with neuroretinal rim area, cup area was significantly (P < 0.01) more strongly correlated with disc area and the regression line was steeper in the whole optic disc and in each disc segment. The regional distribution of the widest rim part and smallest rim part was independent of disc size.
The increase of rim area and cup area with increasing disc size differs between various disc regions. Because cup area increases more than rim area with increasing disc size, correction for disc size may be more important for segmental cup area than for segmental rim area. The rim shape with respect to the location of the smallest or broadest rim part is independent of disc size.
评估视盘大小对健康眼睛节段性神经视网膜边缘面积的影响。
本研究纳入了193例患有生理性视盘凹陷的健康患者的193只眼睛。在15度彩色立体视盘幻灯片上，对视盘面积和神经视网膜边缘面积进行形态测量，将视盘分为36个径向节段，每个节段为10度。
节段性边缘面积与视盘面积的相关性在视盘下方区域显著最强（P < 0.01），回归线最陡，而在颞侧视盘区域值最低。与边缘数据互补的是，节段性杯盘面积与视盘面积的相关性在颞侧视盘区域显著最强（P < 0.01），回归线最陡，而在下方视盘区域值最低。与神经视网膜边缘面积相比，杯盘面积与视盘面积的相关性显著更强（P < 0.01），在整个视盘及每个视盘节段中回归线更陡。最宽边缘部分和最窄边缘部分的区域分布与视盘大小无关。
视盘大小增加时，边缘面积和杯盘面积的增加在不同视盘区域有所不同。由于随着视盘大小增加杯盘面积比边缘面积增加得更多，对视盘大小进行校正对于节段性杯盘面积可能比对节段性边缘面积更重要。边缘形状相对于最窄或最宽边缘部分的位置与视盘大小无关。
