Xu L, Wang Y, Yang H, Zhang L, Jonas J B
Beijing Institute of Ophthalmology, 17 Hougou Street, Chong Wen Men, 100005 Beijing, China.
Br J Ophthalmol. 2007 Dec;91(12):1616-9. doi: 10.1136/bjo.2007.121509. Epub 2007 Jun 27.
To measure the size of the neuroretinal rim, the major variable in the quantitative analysis of the optic nerve head, and its correlations in adult Chinese in a population based setting.
The Beijing eye study-a population based, cross sectional cohort study-included 4439 subjects from among 5324 of age of 40+ years invited to participate (response rate 83.4%). This study included a random sample of 781 subjects with normal intraocular pressure (IOP), normal visual fields, and a normal optic nerve head; and a random sample of 84 subjects with an IOP >21 mm Hg. Colour optic disc photographs (30 degrees ) were examined morphometrically.
In the normal group, the mean (SD) neuroretinal rim area was 1.70 (0.30) mm(2). It was significantly correlated with optic disc area (rim area = 0.43*disc area+0.67; p<0.001). It was not significantly associated with age, sex, or a known diagnoses of diabetes mellitus, arterial hypertension or hypotension, hyperlipidaemia, coronary heart disease, or cerebral haemorrhage.
In adult Chinese, the neuroretinal rim area measures 1.70 (0.30) mm(2) on optic disc photographs. It is statistically independent of age. Compared with data from studies in Western countries, the neuroretinal rim is larger in adult Chinese than in adult white populations, corresponding to a larger optic disc size in the Chinese.
测量神经视网膜边缘的大小，这是视神经乳头定量分析中的主要变量，并在基于人群的研究中探讨其在成年中国人中的相关性。
北京眼病研究是一项基于人群的横断面队列研究，邀请了5324名年龄在40岁及以上的受试者参与，其中4439人纳入研究（应答率83.4%）。本研究包括781名眼压正常、视野正常且视神经乳头正常的受试者随机样本，以及84名眼压>21mmHg的受试者随机样本。对彩色视盘照片（30度）进行形态测量。
在正常组中，神经视网膜边缘面积的平均值（标准差）为1.70（0.30）mm²。它与视盘面积显著相关（边缘面积 = 0.43×视盘面积 + 0.67；p<0.001）。它与年龄、性别或已知的糖尿病、动脉高血压或低血压、高脂血症、冠心病或脑出血诊断无显著关联。
在成年中国人中，视盘照片上神经视网膜边缘面积为1.70（0.30）mm²。它在统计学上与年龄无关。与西方国家的研究数据相比，成年中国人的神经视网膜边缘比成年白种人更大，这与中国人视盘尺寸更大相对应。
