Kasiske B L, Vazquez M A, Harmon W E, Brown R S, Danovitch G M, Gaston R S, Roth D, Scandling J D, Singer G G
Division of Nephrology, Hennepin County Medical Center, University of Minnesota, Minneapolis 55415, USA.
J Am Soc Nephrol. 2000 Oct;11 Suppl 15:S1-86.
Many complications after renal transplantation can be prevented if they are detected early. Guidelines have been developed for the prevention of diseases in the general population, but there are no comprehensive guidelines for the prevention of diseases and complications after renal transplantation. Therefore, the Clinical Practice Guidelines Committee of the American Society of Transplantation developed these guidelines to help physicians and other health care workers provide optimal care for renal transplant recipients. The guidelines are also intended to indirectly help patients receive the access to care that they need to ensure long-term allograft survival, by attempting to systematically define what that care encompasses. The guidelines are applicable to all adult and pediatric renal transplant recipients, and they cover the outpatient screening for and prevention of diseases and complications that commonly occur after renal transplantation. They do not cover the diagnosis and treatment of diseases and complications after they become manifest, and they do not cover the pretransplant evaluation of renal transplant candidates. The guidelines are comprehensive, but they do not pretend to cover every aspect of care. As much as possible, the guidelines are evidence-based, and each recommendation has been given a subjective grade to indicate the strength of evidence that supports the recommendation. It is hoped that these guidelines will provide a framework for additional discussion and research that will improve the care of renal transplant recipients.
如果能早期发现,肾移植后的许多并发症是可以预防的。针对普通人群疾病的预防已经制定了指南,但尚无关于预防肾移植后疾病和并发症的全面指南。因此,美国移植学会临床实践指南委员会制定了这些指南,以帮助医生和其他医护人员为肾移植受者提供最佳护理。这些指南还旨在通过试图系统地界定这种护理所涵盖的内容,间接帮助患者获得确保长期移植肾存活所需的护理。这些指南适用于所有成人和儿童肾移植受者,涵盖肾移植后常见疾病和并发症的门诊筛查与预防。它们不涵盖疾病和并发症出现后的诊断与治疗,也不涵盖肾移植候选者的移植前评估。这些指南内容全面,但并不试图涵盖护理的方方面面。这些指南尽可能以证据为基础,每项建议都给出了一个主观等级,以表明支持该建议的证据强度。希望这些指南将为进一步的讨论和研究提供一个框架,从而改善肾移植受者的护理。