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欧洲肾移植最佳实践指南。第四部分:移植受者的长期管理。IV.6.3. 肾移植后的癌症风险。实体器官癌症:预防与治疗。

European best practice guidelines for renal transplantation. Section IV: Long-term management of the transplant recipient. IV.6.3. Cancer risk after renal transplantation. Solid organ cancers: prevention and treatment.

出版信息

Nephrol Dial Transplant. 2002;17 Suppl 4:32, 34-6.

Abstract

J. All renal transplant recipients should have regular ultrasonography of their native kidneys (when applicable) for screening of renal cell carcinomas, which are observed at much higher incidence in both dialysed and transplant patients. K. Guidelines published for screening and prevention of solid organ cancers in the general population should be strictly applied to transplant recipients, who are in general at higher cancer risk, but would benefit equally or even greater. L. All male renal transplant recipients aged 50 and over should have a yearly prostate specific antigen (PSA) test prior to a regular digital rectal examination. M. All female renal transplant recipients should have a yearly cervical (PAP) smear together with regular pelvic examination and regular mammography, according to national recommendations where available. N. All renal transplant recipients should undergo a faecal occult-blood testing as a screening for colorectal cancer and other (pre-malignant) lesions, according to national recommendations where available. O. In all these conditions, it is recommended to reduce immunosuppression whenever possible.

摘要

J. 所有肾移植受者(如适用)均应定期对其自身肾脏进行超声检查,以筛查肾细胞癌,透析患者和移植患者中肾细胞癌的发病率均明显更高。K. 为普通人群制定的实体器官癌症筛查和预防指南应严格适用于移植受者,他们总体上癌症风险较高,但同样会从中受益甚至受益更大。L. 所有50岁及以上的男性肾移植受者应在定期直肠指检前每年进行一次前列腺特异性抗原(PSA)检测。M. 所有女性肾移植受者应根据国家建议(如有)每年进行一次宫颈涂片检查(巴氏涂片),同时进行定期盆腔检查和定期乳房X光检查。N. 所有肾移植受者应根据国家建议(如有)进行粪便潜血检测,以筛查结直肠癌和其他(癌前)病变。O. 在所有这些情况下,建议尽可能减少免疫抑制。

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