未分类急性淋巴细胞白血病细胞上HL-B同种异体抗原的出现。
The occurrence of the HL-B alloantigens on the cells of unclassified acute lymphoblastic leukemias.
作者信息
Fu S M, Winchester R J, Kunkel H G
出版信息
J Exp Med. 1975 Nov 1;142(5):1334-8. doi: 10.1084/jem.142.5.1334.
Abstract
Six cases of acute lymphoblastic leukemia were studied by a variety of T- and B-lymphocyte surface markers. Two appeared to represent T-cell leukemias with the lymphoblasts forming sheep erythrocyte rosettes. The other four lacked all the usual membrane markers. However, indirect immunofluorescence with alloantisera detected the presence of the Ia-related HL-B antigens on the cells of the latter four cases; these antigens were absent in the first two cases. The primary association of the HL-B antigens with B cells raises the possibility that the positive group of cases are of B-cell lineage.
摘要
通过多种T淋巴细胞和B淋巴细胞表面标志物对6例急性淋巴细胞白血病进行了研究。其中2例似乎代表T细胞白血病，其淋巴母细胞形成绵羊红细胞玫瑰花结。另外4例缺乏所有常见的膜标志物。然而，用同种抗血清进行的间接免疫荧光检测发现，后4例患者的细胞上存在与Ia相关的HL - B抗原；前2例中不存在这些抗原。HL - B抗原与B细胞的主要关联增加了阳性病例组为B细胞系的可能性。
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The occurrence of the HL-B alloantigens on the cells of unclassified acute lymphoblastic leukemias.未分类急性淋巴细胞白血病细胞上HL-B同种异体抗原的出现。
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本文引用的文献
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Scand J Immunol. 1974;3(6):847-51. doi: 10.1111/j.1365-3083.1974.tb01322.x.
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J Exp Med. 1974 Feb 1;139(2):451-6. doi: 10.1084/jem.139.2.451.
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Specific properties of human B and T lymphocytes and alterations in disease.人类B淋巴细胞和T淋巴细胞的特定特性以及疾病中的改变。
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Detection of antigens specific for B-lymphoid cultured cell lines with human alloantisera.用人同种抗血清检测B淋巴细胞培养细胞系的特异性抗原。
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