Warner J O, Jones C A, Kilburn S A, Vance G H, Warner J A
Child Health, University of Southampton/Southampton General Hospital, UK.
Pediatr Allergy Immunol. 2000;11 Suppl 13:6-8. doi: 10.1034/j.1399-3038.2000.00501.x.
Allergy has a very strong hereditary component but even in identical twins, concordance for the development of allergic disease can be as low as 50%. This suggests that there is a very strong environmental influence on manifestations of sensitization. To what extent environment might have an influence on the ontogeny of sensitization antenatally has hitherto not been a focus of much research. However, circumstantial evidence suggests that this may be important.
过敏具有很强的遗传因素，但即使是同卵双胞胎，患过敏性疾病的一致性也可能低至50%。这表明环境对致敏表现有很强的影响。环境在多大程度上可能对产前致敏的发生发展产生影响，迄今为止尚未成为很多研究的重点。然而，间接证据表明这可能很重要。
