Adachi J A, Ostrosky-Zeichner L, DuPont H L, Ericsson C D
Division of Infectious Diseases, Department of Internal Medicine, University of Texas-Houston Medical School, Houston, TX 77030, USA.
Clin Infect Dis. 2000 Oct;31(4):1079-83. doi: 10.1086/318119. Epub 2000 Oct 25.
Over 7 million cases of traveler's diarrhea, defined as the passage of > or = 3 unformed stools in a 24-h period, occur each year among visitors to developing countries. Bacterial enteric pathogens are the most common etiologic agents isolated. Preliminary clinical results for patients with diarrhea predominantly caused by Campylobacter species have shown that azithromycin may be an effective alternative to fluoroquinolones for the treatment of traveler's diarrhea.
每年有超过700万例旅行者腹泻病例发生在前往发展中国家的游客中,旅行者腹泻定义为24小时内排出≥3次不成形粪便。细菌性肠道病原体是最常见的分离出的病原体。针对主要由弯曲杆菌属引起腹泻的患者的初步临床结果表明,阿奇霉素可能是治疗旅行者腹泻的一种有效的氟喹诺酮类替代药物。