糖尿病患者的眼动脉搏动幅度
Ocular pulse amplitude in diabetes mellitus.
作者信息
Schmidt K G, von Rückmann A, Kemkes-Matthes B, Hammes H P
机构信息
Nuffield Laboratory of Ophthalmology, Walton Street, University of Oxford, UK.
出版信息
Br J Ophthalmol. 2000 Nov;84(11):1282-4. doi: 10.1136/bjo.84.11.1282.
Abstract
BACKGROUND
The influence of diabetes mellitus on ocular pulse amplitude (OPA), an indirect measure of choroidal perfusion, is unclear.
METHODS
OPA, using the Langham ocular blood flow (OBF) system, applanation intraocular pressure (IOP), systemic blood pressure (BP), heart rate, and haemoglobin (Hb) A(1c) were measured in patients with insulin dependent diabetes mellitus (IDDM) with no (DR-0, n = 22) non-proliferative (DR-1, n = 24), and proliferative (DR-2, n = 18) diabetic retinopathy.
RESULTS
Neither local (OPA, IOP) nor systemic perfusion parameters (BPs, HR) nor HbA(1c) were significantly altered in DR-0, DR-1, or DR-2 IDDM patients.
CONCLUSION
Choroidal circulation remains unaffected as diabetic retinopathy advances.
摘要
背景
糖尿病对视脉振幅（OPA）的影响尚不清楚，OPA是脉络膜灌注的一种间接测量指标。
方法
使用兰厄姆眼血流（OBF）系统测量胰岛素依赖型糖尿病（IDDM）患者的OPA、压平眼压（IOP）、全身血压（BP）、心率和血红蛋白（Hb）A1c，这些患者分别无糖尿病视网膜病变（DR-0，n = 22）、非增殖性糖尿病视网膜病变（DR-1，n = 24）和增殖性糖尿病视网膜病变（DR-2，n = 18）。
结果
DR-0、DR-1或DR-2的IDDM患者的局部（OPA、IOP）、全身灌注参数（BP、HR）或HbA1c均无显著变化。
结论
随着糖尿病视网膜病变的进展，脉络膜循环仍未受影响。
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