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健康维护组织中酒精与药物治疗的结果及成本:日间医院与传统门诊治疗方案对比

The outcome and cost of alcohol and drug treatment in an HMO: day hospital versus traditional outpatient regimens.

作者信息

Weisner C, Mertens J, Parthasarathy S, Moore C, Hunkeler E M, Hu T, Selby J V

机构信息

Kaiser Division of Research, Oakland, CA 94611, USA.

出版信息

Health Serv Res. 2000 Oct;35(4):791-812.

Abstract

OBJECTIVE

To compare outcome and cost-effectiveness of the two primary addiction treatment options, day hospitals (DH) and traditional outpatient programs (OP) in a managed care organization, in a population large enough to examine patient subgroups.

DATA SOURCES

Interviews with new admissions to a large HMO's chemical dependency program in Sacramento, California between April 1994 and April 1996, with follow-up interviews eight months later. Computerized utilization and cost data were collected from 1993 to 1997.

STUDY DESIGN

Design was a randomized control trial of adult patients entering the HMO's alcohol and drug treatment program (N = 668). To examine the generalizability of findings as well as self-selection factors, we also studied patients presenting during the same period who were unable or unwilling to be randomized (N = 405). Baseline interviews characterized type of substance use, addiction severity, psychiatric status, and motivation. Follow-up interviews were conducted at eight months following intake. Breathanalysis and urinalysis were conducted. Program costs were calculated.

DATA COLLECTION

Interview data were merged with computerized utilization and cost data.

PRINCIPAL FINDINGS

Among randomized subjects, both study arms showed significant improvement in all drug and alcohol measures. There were no differences overall in outcomes between DH and OP, but DH subjects with midlevel psychiatric severity had significantly better outcomes, particularly in regard to alcohol abstinence (OR = 2.4; 95% CI = 1.2, 4.9). The average treatment costs were $1,640 and $895 for DH and OP programs, respectively. In the midlevel psychiatric severity group, the cost of obtaining an additional person abstinent from alcohol in the DH cohort was approximately $5,464. Among the 405 self-selected subjects, DH was related to abstinence (OR = 2.1; 95% CI = 1.3, 3.5).

CONCLUSIONS

Although significant benefits of the DH program were not found in the randomized study, DH treatment was associated with better outcomes in the self-selected group. However, for subjects with mid-level psychiatric severity in both the randomized and self-selected samples, the DH program produced higher rates of abstention and was more cost-effective. Self-selection in studies that randomize patients to services requiring very different levels of commitment may be important in interpreting findings for clinical practice.

摘要

目的

在一个管理式医疗组织中,比较日间医院(DH)和传统门诊项目(OP)这两种主要成瘾治疗方案的治疗效果和成本效益,研究对象数量足够多,以便对患者亚组进行考察。

数据来源

对1994年4月至1996年4月期间加利福尼亚州萨克拉门托市一家大型健康维护组织(HMO)化学依赖项目的新入院患者进行访谈,并在八个月后进行随访访谈。收集了1993年至1997年的计算机化利用和成本数据。

研究设计

设计为对进入HMO酒精和药物治疗项目的成年患者进行的随机对照试验(N = 668)。为了检验研究结果的普遍性以及自我选择因素,我们还研究了同期无法或不愿被随机分组的患者(N = 405)。基线访谈描述了物质使用类型、成瘾严重程度、精神状态和动机。在入院八个月后进行随访访谈。进行了呼气分析和尿液分析。计算了项目成本。

数据收集

访谈数据与计算机化利用和成本数据合并。

主要发现

在随机分组的受试者中,两个研究组在所有药物和酒精指标上均显示出显著改善。DH组和OP组的总体治疗效果没有差异,但中度精神严重程度的DH组受试者治疗效果明显更好,尤其是在戒酒方面(比值比[OR] = 2.4;95%置信区间[CI] = 1.2, 4.9)。DH项目和OP项目的平均治疗成本分别为1640美元和895美元。在中度精神严重程度组中,DH组中每多戒酒一人的成本约为5464美元。在405名自我选择的受试者中,DH组与戒酒相关(OR = 2.1;95% CI = [1.3, 3.5])。

结论

尽管在随机研究中未发现DH项目有显著益处,但在自我选择组中,DH治疗与更好的治疗效果相关。然而,对于随机分组和自我选择样本中中度精神严重程度的受试者,DH项目戒酒率更高且更具成本效益。在将患者随机分配到需要不同投入水平的服务的研究中,自我选择可能对解释临床实践中的研究结果很重要。

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