Garg P, Nandy R K, Chaudhury P, Chowdhury N R, De K, Ramamurthy T, Yamasaki S, Bhattacharya S K, Takeda Y, Nair G B
Department of Microbiology, National Institute of Cholera and Enteric Diseases, Calcutta 700 010, India.
J Clin Microbiol. 2000 Nov;38(11):4249-53. doi: 10.1128/JCM.38.11.4249-4253.2000.
The toxigenic Inaba serotype of Vibrio cholerae O1 biotype El Tor reappeared in India in 1998 and 1999, almost 10 years after its last dominance in Calcutta in 1989. Extensive molecular characterization by ribotyping, restriction fragment length polymorphism, and pulsed-field gel electrophoresis indicated that recent Inaba strains are remarkably different from the earlier Inaba strains but are very similar to the prevailing V. cholerae O1 Ogawa El Tor biotype strains. The antibiograms of the Inaba strains were also similar to those of the recent V. cholerae Ogawa strains. These V. cholerae O1 Inaba strains appear to have evolved from the currently prevailing Ogawa strains and are likely to dominate in the coming years.
霍乱弧菌O1生物型埃尔托的产毒性稻叶血清型于1998年和1999年在印度再次出现,距其上次于1989年在加尔各答占主导地位近10年。通过核糖体分型、限制性片段长度多态性和脉冲场凝胶电泳进行的广泛分子特征分析表明,近期的稻叶菌株与早期的稻叶菌株明显不同,但与流行的霍乱弧菌O1小川埃尔托生物型菌株非常相似。稻叶菌株的抗菌谱也与近期霍乱弧菌小川菌株的抗菌谱相似。这些霍乱弧菌O1稻叶菌株似乎是从目前流行的小川菌株进化而来的,并且可能在未来几年占主导地位。