Fives-Taylor P, Novotny C P
J Bacteriol. 1976 Feb;125(2):540-44. doi: 10.1128/jb.125.2.540-544.1976.
The effects of rifampin and streptolydigin, inhibitors of ribonucleic acid (RNA) synthesis, on the production of F pili by Escherichia coli were studied by electron microscopy. The inhibition of RNA synthesis reduces the number of new pili produced by depiliated cells, but does not affect their length or the number of pili present at the time of inhibition or the retraction of pili. We suggest that the rifampin-sensitive step may be linked to the establishement of a site for pili production. Evidence is provided that chloramphenicol inhibits retraction. We suggest that retraction requires some protein whose pool size is limited.
通过电子显微镜研究了核糖核酸（RNA）合成抑制剂利福平与链霉溶菌素对大肠杆菌F菌毛产生的影响。RNA合成的抑制减少了去菌毛细胞产生的新菌毛数量，但不影响其长度、抑制时存在的菌毛数量或菌毛的回缩。我们认为利福平敏感步骤可能与菌毛产生位点的建立有关。有证据表明氯霉素抑制菌毛回缩。我们认为菌毛回缩需要一些总量有限的蛋白质。
