自身免疫性孕酮性荨麻疹

Autoimmune progesterone urticaria.

作者信息

Vasconcelos C, Xavier P, Vieira A P, Martinho M, Rodrigues J, Bodas A, Barros M A, Mesquita-Guimarães J

机构信息

Department of Dermatology and Venereology, University Hospital of São João, Porto, Portugal.

出版信息

Gynecol Endocrinol. 2000 Aug;14(4):245-7. doi: 10.3109/09513590009167688.

DOI:10.3109/09513590009167688

PMID:11075293

Abstract

Autoimmune progesterone dermatitis is a rare cutaneous disorder characterized by recurrent and cyclic skin eruption with variable morphology, occurring during the luteal phase. A case of autoimmune progesterone urticaria in a 47-year-old woman is reported. An intradermal progestin test revealed a strong reactivity against this hormone. Treatment with tamoxifen and leuprolide acetate induced only a partial remission of urticaria. Bilateral oophorectomy was performed with absolute clearing of cutaneous lesions.

摘要

自身免疫性孕酮性皮炎是一种罕见的皮肤疾病，其特征为在黄体期出现形态各异的复发性、周期性皮肤疹。本文报告了一例47岁女性的自身免疫性孕酮性荨麻疹病例。皮内孕激素试验显示对该激素有强烈反应。他莫昔芬和醋酸亮丙瑞林治疗仅使荨麻疹部分缓解。双侧卵巢切除术实施后皮肤病变完全消除。