Tekkis P P, Kocher H M, Bentley A J, Cullen P T, South L M, Trotter G A, Ellul J P
Maidstone General Hospital, Kent, United Kingdom.
Dis Colon Rectum. 2000 Nov;43(11):1528-32, discusssion 1532-4. doi: 10.1007/BF02236732.
The original Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity and the more recent Portsmouth predictor equation for mortality scoring systems were developed to provide risk-adjusted mortality rates in general surgery. The aim of this study was to compare crude and risk-adjusted operative mortality rates among four surgeons using the above scoring systems and assess their applicability for patients scored retrospectively.
A total of 505 consecutive patients undergoing major gastrointestinal surgery were analyzed; 65 percent underwent colorectal, 27.5 percent underwent upper gastrointestinal, and 7.5 percent underwent small-bowel surgery. The observed:predicted mortality ratios using the Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity and Portsmouth predictor equation for mortality scoring systems were calculated for each surgeon.
The actual overall operative mortality rate was 11.1 percent (elective was 3.9 percent, and emergency was 25.1 percent). The Portsmouth predictor equation for mortality equation predicted a mortality rate of 11.3 percent (P = 0.51). However, the Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity scoring system was found to overpredict death by a factor of two: 21.5 percent (P < 0.001). Mortality rates among the four surgeons varied from 7.6 to 14.7 percent but depended on the proportion of elective vs. emergency surgery. The observed:predicted ratio for Portsmouth predictor equation for mortality was close to unity (0.905-1.067) for all surgeons, but it was 0.45 to 0.56 for Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity.
The Portsmouth predictor equation for mortality equation seems to be a more accurate predictor of mortality in gastrointestinal surgery. It would seem to provide the best choice for analyzing operative mortality rates for individual surgeons, taking into account variation in case mix and fitness of patients even when scored retrospectively. This has important implications for the future assessment of surgeons' clinical standards and the assessment of quality of surgical care.
最初的用于计算死亡率和发病率的生理与手术严重程度评分(POSSUM)以及更新的用于死亡率评分系统的朴茨茅斯预测方程,旨在提供普通外科手术中经风险调整的死亡率。本研究的目的是使用上述评分系统比较四位外科医生的粗手术死亡率和经风险调整的手术死亡率,并评估其对回顾性评分患者的适用性。
对总共505例连续接受重大胃肠手术的患者进行分析;65%接受结直肠手术,27.5%接受上消化道手术,7.5%接受小肠手术。使用用于计算死亡率和发病率的生理与手术严重程度评分以及用于死亡率评分系统的朴茨茅斯预测方程,计算每位外科医生的观察到的与预测的死亡率之比。
实际总体手术死亡率为11.1%(择期手术为3.9%,急诊手术为25.1%)。朴茨茅斯死亡率预测方程预测死亡率为11.3%(P = 0.51)。然而,发现用于计算死亡率和发病率的生理与手术严重程度评分系统高估死亡率达两倍:21.5%(P < 0.001)。四位外科医生的死亡率在7.6%至14.7%之间变化,但取决于择期手术与急诊手术的比例。朴茨茅斯死亡率预测方程的观察到的与预测的比率对所有外科医生而言接近1(0.905 - 1.067),但用于计算死亡率和发病率的生理与手术严重程度评分的该比率为0.45至0.56。
朴茨茅斯死亡率预测方程似乎是胃肠手术中更准确的死亡率预测指标。考虑到病例组合和患者健康状况的差异,即使在回顾性评分时,它似乎也是分析个体外科医生手术死亡率的最佳选择。这对未来外科医生临床标准的评估以及手术护理质量的评估具有重要意义。